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Een zeldzame oorzaak van dementie: de bestralingsencephalopathie

Published online by Cambridge University Press:  15 April 2016

N. van de Weg ,
F.R.J. Verhey ,
P J.M. Raedts  and
F W. Vreeling
N. van de Weg
Affiliation:
psychiater (destijds: i.o, Academisch Ziekenhuis Maastricht)
F.R.J. Verhey*
Affiliation:
zenuwarts, afdeling Psychiatrie, Academisch Ziekenhuis Maastricht
P J.M. Raedts
Affiliation:
zenuwarts, afdeling Neurologie, Elckerlyk Ziekenhuis, Helmond
F W. Vreeling
Affiliation:
neuroloog, afdeling Neurologie, Academisch Ziekenhuis Maastricht
*
Afdeling Psychiatrie, Academisch Ziekenhuis Maastricht, Postbus 5800, 6202 AZ Maastricht, tel +31-43-3877444, fax, +31-43-3875444, e-mail:, f.verhey@np.unimaas.nl
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Summary

We describe the clinical history of a 49-year old woman, who demonstrated progressive personality changes more than twenty years after radiation of a pituitary adenoma (prolactinoma), with apathy, loss of initiative, memory deficits, postural instability, dysarthria and faecal incontinence. Neuropsychological assessment showed impulsivity, loss of overview, desinhibition, fluctuating deficits of attention, and memory disturbances. MRI-scanning of the brain revealed a cystic lesion along the right ventricle. The clinical picture and the findings of the other investigations are typical for dementia due to radiation encephalopathy. Such a long period between radiation and cognitive deterioration is rare, although it has been described before.

Keywords

dementiaradiation encephalopathypituitary adenoma
Type
Articles
Information
Acta Neuropsychiatrica , Volume 13 , Issue 3 , September 2001 , pp. 76 - 78
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 2001

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References

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