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Fluoxetine-induced tardive dyskinesia in a patient with Parkinson's disease

Published online by Cambridge University Press:  24 June 2014

Deshandra M. Raidoo
Deshandra M. Raidoo*
Affiliation:
Sioux Falls Veterans Affairs Health Care System, Sioux Falls, South Dakota, USA Department of Psychiatry, Sanford School of Medicine, University of South Dakota, Sioux Falls, South Dakota, USA
*
Professor Deshandra M. Raidoo, Sioux Falls Veterans Affairs Health Care System, 2501 W 22nd Street, Sioux Falls, South Dakota 57117, USA. Tel: +6053363230; Fax: +6053335387; E-mail: draidoo@usd.edu
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Extract

Background: This is a report of a 66-year-old male with Parkinson's disease (PD), depression and anxiety who developed tardive dyskinesia (TD) while on fluoxetine.

Methods: The patient underwent psychiatric, neurological and neuroimaging examination.

Results: The patient's neuroimaging examination was normal, his psychiatric assessment revealed depression and anxiety, and his neurological evaluation diagnosed only mild PD. The patient's TD resolved when fluoxetine was discontinued and recurred upon re-exposure.

Conclusion: This case shows that fluoxetine as monotherapy can be associated with TD especially in patients with concomitant PD. Clinicians must be aware of this side-effect and monitor for features of TD due to antidepressants that are often used to treat comorbid depression in patients with PD.

Keywords

EPSfluoxetineParkinson's diseasetardive dyskinesias
Type
Case Reports
Information
Acta Neuropsychiatrica , Volume 24 , Issue 5 , October 2012 , pp. 306 - 309
Copyright
Copyright © Cambridge University Press 2012

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