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Feasibility Studies of X-ray Fluorescence as a Method for the In Vivo Determination of Platinum and Other Heavy Metals

Published online by Cambridge University Press:  06 March 2019

J. Dutton ,
C. J. Evans ,
S. B. Samat ,
W. D. Morgan  and
A. Sivyer
J. Dutton
Affiliation:
Department of Physics University College of Swansea Singleton Park, Swansea SA2 8PP, UK
C. J. Evans
Affiliation:
Department of Physics University College of Swansea Singleton Park, Swansea SA2 8PP, UK
S. B. Samat
Affiliation:
Department of Physics University College of Swansea Singleton Park, Swansea SA2 8PP, UK
W. D. Morgan
Affiliation:
Department of Medical Physics Singleton Hospital Swansea SA2 8QA, UK
A. Sivyer
Affiliation:
Department of Medical Physics Singleton Hospital Swansea SA2 8QA, UK
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Extract

There has recently been growing interest in various atomic and nuclear techniques for the measurement of elements in the body. This has arisen through the realisation that (a) clinically-important amounts of toxic elements can be absorbed as a result of low-level environmental exposure, and (b) important information about the nutritional status of a patient can be obtained from measurements of major body elements. Where such information can be obtained by taking samples, a very wide range of analytical techniques is available, some capable of a sensitivity measured in parts-per-billion. Sampling is not possible, however, when the whole-body content (e.g. of nitrogen) is required, and is clinically undesirable when the element in question is concentrated in particular organs, for example as lead accumulates in the bones, and cadmium and many other toxic elements accumulate in the kidneys. It is in such cases that the various in vivo techniques are particularly important.

Type
V. Applications of XRF and XRD to Life Sciences and the Environment
Information
Advances in X-Ray Analysis , Volume 28: Thirty-Third Annual Conference on Applications of X-ray Analysis, July 30 - August 3, 1984 , 1984 , pp. 145 - 154
Copyright
Copyright © International Centre for Diffraction Data 1984

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References

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