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Gonadotropin Levels in Mothers Who Have Had Two Sets of DZ Twins

Published online by Cambridge University Press:  01 August 2014

N.G. Martin*
Affiliation:
Department of Population Biology, Research School of Biological Sciences, Australian National University, Canberra
J.L. El Beaini
Affiliation:
Department of Obstetrics & Gynaecology, Charing Cross Hospital, London
M.E. Olsen
Affiliation:
Department of Population Biology, Research School of Biological Sciences, Australian National University, Canberra
A.S. Bhatnagar
Affiliation:
Department of Obstetrics & Gynaecology, Medical College of Virginia, Virginia Commonwealth University, Richmond
D. Macourt
Affiliation:
Department of Obstetrics & Gynaecology, University of New South Wales, Sydney, Australia
*
Department of Human Genetics, Box 33, MCV Station, Richmond, VA 23298, USA

Abstract

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Serum gonadotropin, estradiol, prolactin and alpha-1-antitrypsin levels were measured in the first four days of the menstrual cycle in 14 women who were cycling normally. FSH, and to a lesser extent LH levels, were significantly higher in a group of 8 women who had at least one set of DZ twins (6 of whom had 2 sets) than in a control group of 6 women with no DZ twins. Estradiol levels also tended to be higher in mothers of twins but there were no significant differences in prolactin or alpha-1-antitrypsin concentrations. There were no differences between the means of the two groups in age, height, weight or number of pregnancies.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1984

References

REFERENCES

1.Bulmer, MG (1970): The Biology of Twinning in Man. Oxford: Clarendon Press.Google Scholar
2.Clark, P, Martin, NG (1982): An excess of the PiS allele in dizygotic twins and their mothers. Hum Genet 61:171–4.CrossRefGoogle ScholarPubMed
3.diZerega, GS, Turner, CK, Stouffer, RL, Anderson, LD, Channing, CP, Hodgen, GD (1981): Suppression of follicle stimulating hormone dependent folliculogenesis during the primate ovarian cycle. J Clin Endocrinol Metabol 52:451–6.Google Scholar
4.Garza, R, Burns, B, Manlimos, F, Abraham, G (1975): Radioimmunoassay of plasma progesterone without chromatography. Analyt Letters 8:225232.Google Scholar
5.Gemzell, CA (1965): Induction of ovulation with human gonadotrophins. Rec Prog Horm Res 21:179198.Google Scholar
6.Gemzell, C, Roos, P (1966): Pregnancies following treatment with human gonadotropins. Am J Obstet Gynecol 94:480496.CrossRefGoogle ScholarPubMed
7.Hillier, SG, Reichter, LE, van Hall, EV (1981): Control of preovulatory follicular estrogen biosynthesis in the human ovary. J Clin Endocrinol Metabol 52:847856.CrossRefGoogle ScholarPubMed
8.Hodgen, GD (1982): The dominant ovarian follicle. Fertil Steril 38:281300.Google Scholar
9.McNatty, KP (1982): Ovarian follicular develpment from the onset of luteal regression in humans and sheep. In Rolland et al [16].Google Scholar
10.McNatty, KP, Lun, S, Fannin, J, McDiarmid, JM, Heath, DA (1983): The recruitment of an ovarian follicle for ovulation. In Shizume, , Imura, , Shimizu, (eds): Endocrinology. Amsterdam: Excerpta Medica.Google Scholar
11.Midgley, AR, Sadler, WA (eds) (1979): Ovarian Follicular Development and Function. New York: Raven Press.Google Scholar
12.Milham, S (1964): Pituitary hormone and dizygotic twinning. Lancet 2:566.Google Scholar
13.Nylander, PPS (1973): Serum levels of gonadotrophins in relation to multiple pregnancy in Nigeria. J. Obstet Gynaecol Br Commonw 80:651–3.Google Scholar
14.Nylander, PPS (1978): Causes of high twinning frequencies in Nigeria. In Nance, WE, Allen, G, Parisi, P (eds): Twin Research: Part B, Biology and Epidemiology. New York: AR Liss, p 3545.Google Scholar
15.Nylander, PPS (1979): The twinning incidence in Nigeria. Acta Genet Med Gemellol 28:261–3.Google Scholar
16.Rolland, R, van Hall, EV, Hillier, SG, McNatty, KP, Schoemaker, J (eds) (1982): Follicular Maturation and Ovulation. Amsterdam: Excerpta Medica.Google Scholar
17.Schumacher, GFB, Pearl, MJ (1968): Alpha-1-antitrypsin in cervical mucus. Fertil Steril 19:91–9.CrossRefGoogle ScholarPubMed
18.Segreti, WO, Winter, PM, Nance, WE (1978): Familial studies of monozygotic twinning. In Nance, WE, Allen, G, Parisi, P (eds): Twin Research: Part B, Biology and Epidemiology. New York: AR Liss, p 5560.Google Scholar
19.Shapiro, RL, Zemek, L, Shulman, MJ (1978): Familial monozygotic twinning. In Nance, WE, Allen, G, Parisi, P (eds): Twin Research: Part B, Biology and Epidemiology, New York: AR Liss, p 61–3.Google Scholar
20.Soma, H, Masomai, T, Takashi, K, Tsuneo, A, Kazuo, T (1975): Serum gonadotrophin levels in Japanese women. Obstet Gynecol 46:311–2.Google Scholar
21.Yen, SSC, Tsai, CC, Naftolin, F, Vanderberg, G, Ajabor, L (1972): Pulsatile patterns of gonadotrophin release in subjects with and without ovarian function. J Clin Endocrinol Metabol 34:671–4.CrossRefGoogle ScholarPubMed