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Housing and Welfare in Laboratory Rats: The Welfare Implications of Social Isolation and Social Contact Among Females

Published online by Cambridge University Press:  11 January 2023

J L Hurst ,
C J Barnard ,
C M Nevison  and
C D West
J L Hurst*
Affiliation:
Division of Animal Husbandry, Faculty of Veterinary Science, University of Liverpool, Leahurst, Neston, South Wirral L64 7TE, UK
C J Barnard
Affiliation:
Behaviour and Ecology Research Group, School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
C M Nevison
Affiliation:
Behaviour and Ecology Research Group, School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
C D West
Affiliation:
Chester Zoo, Chester, Cheshire CH2 1LH, UK
*
† Contact for correspondence and requests for reprints
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Abstract

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Female laboratory rats (Rattus norvegicus; Wistar, Alderley Park) were housed as singletons or groups of three in units of two cages. Units were divided by different types of barrier which allowed varying degrees of social contact across the barrier. Singletons were established either with another singleton on the other side of the barrier or with a group of three as neighbours. Single-housing among females had markedly less effect on time budgeting and pathophysiological measures than among males in a similar, earlier study. In particular, singletons showed a less marked increase in self-directed behaviours, particularly tail chasing, and a smaller reduction in undirected movement around the cage. The smaller reduction in mobility may reflect a greater tendency for singly housed females to attempt escape. Females generally showed much higher levels of escape-oriented behaviours than males and up to a threefold increase in such behaviours when housed singly. Differences in time budgeting and in the apparent significance of social separation between the sexes can be interpreted in terms of differences in socio-sexual strategy and potential mating opportunity, with singleton males responding to their cage as a territory, but singleton females seeking to re-establish social contact. Such an interpretation is consistent with the effects of barrier type on behaviour in singleton females, in which time spent in escape-oriented behaviours reflected the extent to which the barrier facilitated, or frustrated, contact with neighbours.

Keywords

animal welfarefemaleisolationpathophysiologyratRattus norvegicustime budget
Type
Research Article
Information
Animal Welfare , Volume 7 , Issue 2 , May 1998 , pp. 121 - 136
Copyright
© 1998 Universities Federation for Animal Welfare

References

Baenninger, L P 1967 Comparison of behavioural development in socially isolated and grouped rats. Animal Behaviour 15: 312–323CrossRefGoogle ScholarPubMed
Barnard, C J and Hurst, J L 1996 Welfare by design: the natural selection of welfare criteria. Animal Welfare 5: 405–433CrossRefGoogle Scholar
Barnett, S A 1975 The Rat: A Study in Behavior. University of Chicago Press: Chicago, USAGoogle Scholar
Calhoun, J B 1962 The Ecology and Sociology of the Norway Rat. USPHS (United States Public Health Service) Publication No. 1008. Washington, DC: US Government Printing Office, USAGoogle Scholar
Döhler, K D, Gärtner, K, Mühlen, A V and Döhler, U 1977 Activation of anterior pituitary, thyroid and adrenal glands in rats after disturbance stress. Acta Endocrinologica, Copenhagen 86: 489–497Google ScholarPubMed
Fägerstam, L G, Frostell-Karlsson, Å, Karlsson, R, Persson, B and Rönnberg, I 1992 Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis. Journal of Chromatography 597: 397–410CrossRefGoogle ScholarPubMed
Friend, T H, Polan, C E, Gwazdauskas, F C and Heald, C W 1977 Adrenal glucocorticoid response to exogenous adrenocorticotropin mediated by density and social disruption in lactating cows. Journal of Dairy Science 60: 1958–1963CrossRefGoogle ScholarPubMed
Hurst, J L, Barnard, C J, Hare, R, Wheeldon, E B and West, C D 1996 Housing and welfare in laboratory rats: time-budgeting and pathophysiology in single-sex groups. Animal Behaviour 52: 335–360CrossRefGoogle Scholar
Hurst, J L, Barnard, C J, Nevison, C M and West, C D 1997 Housing and welfare in laboratory rats: the welfare implications of social isolation and social contact among males. Animal Welfare 6: 329–397CrossRefGoogle Scholar
Lore, R L and Flannelly, K 1977 Rat societies. Scientific American 236: 106–116CrossRefGoogle ScholarPubMed
Manser, C E 1992 The Assessment of Stress in Laboratory Animals. RSPCA: Horsham, UKGoogle Scholar
McClintock, M K, Anisko, J J and Adler, N T 1982 Group mating among Norway rats II. The social dynamics of copulation: competition cooperation and mate choice. Animal Behaviour 30: 410–425CrossRefGoogle Scholar
McFarland, D J 1989 Problems of Animal Behaviour. Longman: London, UKGoogle Scholar
Mugford, R A and Nowell, N W 1971 The preputial glands as a source of aggression promoting odors in mice. Physiology and Behaviour 6: 247–249CrossRefGoogle Scholar
Ots, I and Horak, P 1996 Great tits Parus major trade health for reproduction. Proceedings of the Royal Society of London Series B 263: 1443–1447Google ScholarPubMed
Pitman, D L, Otterweller, J E and Natelson, B H 1990 Effects of stressor intensity on habituation and sensitization of glucocorticoid responses in rats. Behavioural Neuroscience 104: 28–36Google ScholarPubMed
Restrepo, C and Armorio, A 1987 Chronic stress alters pituitary-adrenal function of prepubertal male rats. Psychoneuroendocrinology 12: 393–395CrossRefGoogle ScholarPubMed
Sapolsky, R M 1983 Individual differences in Cortisol secretory patterns in the wild baboon: role of negative feedback sensitivity. Endocrinology 113: 2263–2267CrossRefGoogle ScholarPubMed
Tuli, J S, Smith, J A and Morton, D B 1994 Corticosterone, adrenal and spleen weight in mice after tail bleeding, and its effect on nearby animals. Laboratory Animals 29: 90–95CrossRefGoogle Scholar
Ziporyn, T and McClintock, M K 1991 Passing as an indicator of social dominance among female wild and domestic Norway rats. Behaviour 118: 26–41CrossRefGoogle Scholar