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Evaluation of the potential use of a meta-population for genomic selection in autochthonous beef cattle populations

Published online by Cambridge University Press:  02 November 2017

E. F. Mouresan ,
J. J. Cañas-Álvarez ,
A. González-Rodríguez ,
S. Munilla ,
J. Altarriba ,
C. Díaz ,
J. A. Baró ,
A. Molina ,
J. Piedrafita  and
L. Varona
E. F. Mouresan
Affiliation:
Departamento de Anatomía, Embriología y Genética, Universidad de Zaragoza, 50013 Zaragoza, Spain
J. J. Cañas-Álvarez
Affiliation:
Grup de Recerca en Remugants, Departament de Ciència Animal 6i dels Aliments, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
A. González-Rodríguez
Affiliation:
Departamento de Anatomía, Embriología y Genética, Universidad de Zaragoza, 50013 Zaragoza, Spain
S. Munilla
Affiliation:
Departamento de Anatomía, Embriología y Genética, Universidad de Zaragoza, 50013 Zaragoza, Spain Departamento de Producción Animal, Facultad de Agronomía, Universidad de Buenos Aires, 1417 CABA, Argentina
J. Altarriba
Affiliation:
Departamento de Anatomía, Embriología y Genética, Universidad de Zaragoza, 50013 Zaragoza, Spain Instituto Agroalimentario de Aragón (IA2), 50013 Zaragoza, Spain
C. Díaz
Affiliation:
Departamento de Mejora Genética Animal, INIA, 28040 Madrid, Spain
J. A. Baró
Affiliation:
Departamento de Ciencias Agroforestales, Universidad de Valladolid, 34004 Palencia, Spain
A. Molina
Affiliation:
MERAGEM, Universidad de Córdoba, 14071 Córdoba, Spain
J. Piedrafita
Affiliation:
Grup de Recerca en Remugants, Departament de Ciència Animal 6i dels Aliments, Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
L. Varona*
Affiliation:
Departamento de Anatomía, Embriología y Genética, Universidad de Zaragoza, 50013 Zaragoza, Spain Instituto Agroalimentario de Aragón (IA2), 50013 Zaragoza, Spain
*
†E-mail: lvarona@unizar.es
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Abstract

This study investigated the potential application of genomic selection under a multi-breed scheme in the Spanish autochthonous beef cattle populations using a simulation study that replicates the structure of linkage disequilibrium obtained from a sample of 25 triplets of sire/dam/offspring per population and using the BovineHD Beadchip. Purebred and combined reference sets were used for the genomic evaluation and several scenarios of different genetic architecture of the trait were investigated. The single-breed evaluations yielded the highest within-breed accuracies. Across breed accuracies were found low but positive on average confirming the genetic connectedness between the populations. If the same genotyping effort is split in several populations, the accuracies were lower when compared with single-breed evaluation, but showed a small advantage over small-sized purebred reference sets over the accuracies of subsequent generations. Besides, the genetic architecture of the trait did not show any relevant effect on the accuracy with the exception of rare variants, which yielded slightly lower results and higher loss of predictive ability over the generations.

Keywords

beef cattlegenomic selectionacross populationaccuracymeta-population
Type
Research Article
Information
animal , Volume 12 , Issue 7 , July 2018 , pp. 1350 - 1357
Copyright
© The Animal Consortium 2017 

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