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LANGUAGE AND DEMENTIA: NEUROPSYCHOLOGICAL ASPECTS

Published online by Cambridge University Press:  01 March 2008

Daniel Kempler  and
Mira Goral
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Abstract

This article reviews recent evidence for the relationship between extralinguistic cognitive and language abilities in dementia. A survey of data from investigations of three dementia syndromes (Alzheimer's disease, semantic dementia and progressive nonfluent aphasia) reveals that, more often than not, deterioration of conceptual organization appears associated with lexical impairments, whereas impairments in executive function are associated with sentence- and discourse-level deficits. These connections between extralinguistic functions and language ability also emerge from the literature on cognitive reserve and bilingualism that investigates factors that delay the onset and possibly the progression of neuropsychological manifestation of dementia.

Type
Research Article
Information
Annual Review of Applied Linguistics , Volume 28 , March 2008 , pp. 73 - 90
Copyright
Copyright © Cambridge University Press 2008

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References

ANNOTATED REFERENCES

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Grossman, M., & Ash, S. (2004) Primary progressive aphasia: A review. Neurocase, 10, 3–18.CrossRefGoogle ScholarPubMed
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Kavé, G. (2003). Morphology in picture descriptions provided by persons with Alzheimer's disease. Journal of Speech, Language, and Hearing Research, 46, 341–352.Google Scholar
Kavé, G., Leonard, C., Cupit, J., & Rochon, E. (2007). Structurally well-formed narrative production in the face of severe conceptual deterioration: A longitudinal case study of a woman with semantic dementia. Journal of Neurolinguistics, 20, 161–177.CrossRefGoogle Scholar
Kavé, G., & Levy, Y. (2003). Sensitivity to gender, person, and tense inflection by persons with Alzheimer's disease. Brain and Language, 87, 267–277.Google Scholar
Kemper, S., Greiner, L. H., Marquiz, J. G., Prenovost, K., & Mitzner, T. L. (2001). Language decline across the life span: Findings from the nun study. Psychology and Aging, 16, 227–239.Google Scholar
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Kempler, D. (1988) Lexical and pantomime abilities in Alzheimer's disease. Aphasiology, 2, 147–159.CrossRefGoogle Scholar
Kempler, D. (2005). Neurocognitive disorders in aging. Thousand Oaks, CA: Sage.Google Scholar
Kempler, D., Almor, A., Tyler, L. K., Andersen, E. S., & MacDonald, M. C. (1998). Sentence comprehension deficits in Alzheimer's disease: A comparison of off-line vs. on-line sentence processing. Brain and Language, 64, 297–316.Google Scholar
Kempler, D., Curtiss, S., & Jackson, C. (1987). Syntactic preservation in Alzheimer's disease. Journal of Speech and Hearing Research, 30, 343–350.Google Scholar
Kempler, D., Metter, E. J., Riege, W. H., Jackson, C. A., Benson, D. F., & Hanson, W. R. (1990). Slowly progressive aphasia: Three cases with language, memory, CT and PET data. Journal of Neurology, Neurosurgery and Neuropsychiatry, 53, 987–993.Google Scholar
Kertesz, A., Davidson, W., McCabe, P., Takagi, K., & Munoz, D. (2003). Primary progressive aphasia: Diagnosis, varieties, evolution. Journal of the International Neuropsychological Society, 9, 710–719.CrossRefGoogle ScholarPubMed
Irigaray, L. (1967). Psycholinguistic approach of the language of the demented. Neuropsychologia, 5, 25–52.Google Scholar
Laine, M., Laakso, M., Vuorinen, E., & Rinne, J. (1998). Coherence and informativeness of discourse in two dementia types. Journal of Neurolinguistics, 11, 79–87.Google Scholar
Manly, J. J., Schupf, N., Tang, M., & Stern, Y. (2005). Cognitive decline and literacy among ethnically diverse elders. Journal of Geriatric Psychiatry and Neurology, 18, 213–217.Google Scholar
Manly, J. J., Touradji, P., Tang, M., & Stern, Y. (2003). Literacy and memory decline among ethnically diverse elders. Journal of Clinical and Experimental Neuropsychology, 5, 680–690.CrossRefGoogle Scholar
Mendez, M. F., & Cummings, J. L. (2003). Dementia: A clinical approach. Philadelphia: Butterworth-Heinemann.Google Scholar
Mendez, M. F., Perryman, K. M., Pontón, M. O., & Cummings, J. L. (1999). Bilingualism and dementia. Journal of Neuropsychiatry and Clinical Neuroscience, 11, 411–412.CrossRefGoogle ScholarPubMed
Mendez, M. F., Saghafi, S., & Clark, D. G. (2004). Semantic dementia in multilingual patients. Journal of Neuropsychiatry and Clinical Neuroscience, 16, 381.Google Scholar
Mesulam, M. M. (1982). Slowly progressive aphasia without generalized dementia. Annals of Neurology, 11, 592–598.Google Scholar
Ober, B. A. (2002). TR and non-RT methodology for semantic priming research with Alzheimer's disease patients: A critical review. Journal of Clinical and Experimental Neuropsychology, 24, 883–912.Google Scholar
Ober, B. A., Jagust, W. J., & Koss, E. (1991). Visuoconstructive performance and regional cerebral glucose metabolism in Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology, 13, 752–772.Google Scholar
Ober, B. A., & Shenaut, G. K. (1999). Well-organized conceptual domains in Alzheimer's disease. Journal of the International Neuropsychological Society, 5, 676–684.Google Scholar
Peelle, J. E., Cooke, A., Moore, P., Vesely, L., & Grossman, M. (2007). Syntactic and thematic components of sentence processing in progressive nonfluent aphasia and nonaphasic frontotemporal dementia. Journal of Neurolinguistics, 20 (6), 482–494.CrossRefGoogle ScholarPubMed
Perneczky, R., Diehl-Schmid, J., Pohl, C., Drzezga, A., & Kurz, A. (2007). Non-fluent progressive aphasia: Cerebral metabolic patterns and brain reserve. Brain Research, 1133, 178–185.CrossRefGoogle ScholarPubMed
Price, C., & Grossman, M. (2005). Verb agreements during on-line sentence processing in Alzheimer's disease and frontotemporal dementia. Brain and Language, 94, 217–232.Google Scholar
Ripich, D. N., & Terrell, B. Y. (1988). Patterns of discourse cohesion and coherence in Alzheimer's disease. Journal of Speech and Hearing Disorders, 53, 8–15.CrossRefGoogle ScholarPubMed
Rochon, E., Kavé, G., Cupit, J., Jokel, R., & Winocur, G. (2004). Sentence comprehension in semantic dementia: A longitudinal case study. Cognitive Neuropsychology, 21, 317–330.Google Scholar
Rochon, E., Waters, G. S., & Caplan, D. (2000). The relationship between measures of working memory and sentence comprehension in patients with Alzheimer's disease. Journal of Speech, Language, and Hearing Research, 43, 395–414.Google Scholar
Rogalski, E., & Mesulam, M. (2007). An update on primary progressive aphasia. Currently Neurology and Neuroscience Reports, 7, 388–392.Google Scholar
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