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The case of the missing brain: Arguments for a role of brain-to-spinal cord pathways in pain facilitation

Published online by Cambridge University Press:  01 September 1997

Linda R. Watkins  and
Steven F. Maier
Linda R. Watkins
Affiliation:
Department of Psychology, University of Colorado at Boulder, Boulder, CO 80309-0345 lwatkins@psych.colorado.edusmaier@psych.coloro.edu
Steven F. Maier
Affiliation:
Department of Psychology, University of Colorado at Boulder, Boulder, CO 80309-0345 lwatkins@psych.colorado.edusmaier@psych.coloro.edu
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Abstract

This commentary on coderre & katz, wiesenfeld-hallin et al., and dickenson focuses on: (a) the brain as an under-recognized contributor to pain facilitation at the spinal cord; (b) these brain-to-spinal pathways being activated by learning or by body infection/inflammation; and (c) the resultant spinal release of anti-analgesic neuropeptides, activators of the NMDA-NO cascade, and activators of glia.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 20 , Issue 3 , September 1997 , pp. 469 - 470
Copyright
© 1997 Cambridge University Press

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