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Central inhibitory dysfunctions in neuropathic pain: What is the relationship between basic science and clinical practice?

Published online by Cambridge University Press:  01 September 1997

Philip J. Siddall
Philip J. Siddall
Affiliation:
University of Cambridge, Department of Anaesthesia, Addenbrooke's Hospital, Cambridge CB2 2QQ United Kingdompjs33@medschl.cam.ac.uk
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Abstract

The possible dysfunction of γ aminobutyric acid (GABA) and opioid inhibitory mechanisms following central and peripheral nervous system injury is an important and potentially useful finding. However, effective clinical application must take into account the specific characteristics of the models used in the studies and the relationship of these models to specific clinical conditions. [dickenson; wiesenfeld-hallin et al.]

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 20 , Issue 3 , September 1997 , pp. 465
Copyright
© 1997 Cambridge University Press

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