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Cue fascination: A new vulnerability in drug addiction

Published online by Cambridge University Press:  29 July 2008

John Sarnecki ,
Rebecca Traynor  and
Michael Clune
John Sarnecki
Affiliation:
Department of Philosophy, University of Toledo, Toledo, OH, 43606-3390
Rebecca Traynor
Affiliation:
Department of Philosophy, University of Toledo, Toledo, OH, 43606-3390
Michael Clune
Affiliation:
Department of English, University of South Florida, Tampa, FL 33620-5550. john.sarnecki@utoledo.eduhttp://homepages.utoledo.edu/jsarnec/index.htmrebecca.traynor@utoledo.edumclune@cas.usf.eduhttp://english.usf.edu/faculty/mclune/
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Abstract

Redish et al. propose a constellation of vulnerabilities inherent in the brain's decision-making system. They allow over-attention to cues a minor role in drug addiction. We think this is inadequate. Using the established links among drug cues, dopamine, and novelty, we propose a fuller account of this key feature of addiction, which we call the phenomenon of cue fascination.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 31 , Issue 4 , August 2008 , pp. 458 - 459
Copyright
Copyright © Cambridge University Press 2008

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References

Berridge, K. C. & Robinson, T. E. (2003) Parsing reward. Trends in Neurosciences 26(9):507–13.CrossRefGoogle ScholarPubMed
Carter, B. L. & Tiffany, S. T. (1999) Meta-analysis of cue-reactivity in addiction research. Addiction 94(3):327–40.CrossRefGoogle ScholarPubMed
Freeman, A. S., Meltzer, L. T. & Bunney, B. S. (1985) Firing properties of substantia nigra dopaminergic neurons in freely moving rats. Life Sciences 36(20):1983–94.CrossRefGoogle ScholarPubMed
Garris, P. A., Kilpatrick, M., Bunin, M. A., Michael, D., Walker, Q. D. & Wightman, R. M. (1999) Dissociation of dopamine release in the nucleus accumbens from intracranial self-stimulation. Nature 398:67–69.CrossRefGoogle ScholarPubMed
Kapur, S., Mizrahi, R. & Li, M. (2005) From dopamine to salience to psychosis – linking biology, pharmacology and phenomenology of psychosis. Schizophrenic Research 79(1):59–68.CrossRefGoogle ScholarPubMed
Kotler, M., Cohen, H., Segman, R., Gritsenko, I., Nemanov, L., Lerer, B., Kramer, I., Zer-Zion, M., Kletz, I. & Ebstein, R. P. (1997) Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects. Molecular Psychiatry 2:251–54.CrossRefGoogle ScholarPubMed
Robinson, T. E. & Berridge, K. C. (1993) The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Research Reviews 18(3):247–336.CrossRefGoogle ScholarPubMed
Robinson, T. E. & Berridge, K. C. (2004) Incentive-sensitization and drug “wanting” (Reply). Psychopharmacology 171:352–53.CrossRefGoogle Scholar
Rosse, R. B., Fay-McCarthy, M., Collins, J. P., Risher-Flowers, D., Alim, T. N. & Deutsch, S. I. (1993) Transient compulsive foraging behavior associated with crack cocaine use. American Journal of Psychiatry 150:155–56.Google ScholarPubMed
Schultz, W. (1998) Predictive reward signal of dopamine neurons. Journal of Neurophysiology 80:1–27.CrossRefGoogle ScholarPubMed
Zinberg, N. E. (1984) Drug, set, and setting: The basis for controlled intoxicant use. Yale University Press.Google Scholar