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E pluribus unum? A new take on addiction by Redish et al.

Published online by Cambridge University Press:  29 July 2008

Thomas Stalnaker  and
Geoffrey Schoenbaum
Thomas Stalnaker
Affiliation:
Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201
Geoffrey Schoenbaum
Affiliation:
Departments of Anatomy and Neurobiology and Psychiatry, University of Maryland School of Medicine, and Adjunct, UMBC Department of Psychology, Baltimore, MD 21201. tstal002@umaryland.eduschoenbg@schoenbaumlab.orghttp://www.schoenbaumlab.org
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Abstract

Neuroscientists and psychologists have proposed a variety of well-supported theories to explain addiction. Many of these theories suggest that addiction results from a single process or dysfunction across all of its forms. The authors of the current review, in contrast, have used a well-defined theoretical account of decision-making to outline the variety of dysfunctions that could account for addictive behavior.

Type
Open Peer Commentary
Information
Behavioral and Brain Sciences , Volume 31 , Issue 4 , August 2008 , pp. 459
Copyright
Copyright © Cambridge University Press 2008

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References

Addolorato, G., Leggio, L., Abenavoli, L., Gasbarrini, G. & the Alcoholism Treatment Study Group (2005) Neurobiochemical and clinical aspects of craving in alcohol addiction: A review. Addictive Behaviors 30(6):1209–24.CrossRefGoogle ScholarPubMed
Bechara, A. (2005) Decision making, impulse control and loss of willpower to resist drugs: A neurocognitive perspective. Nature Neuroscience 8(11):1458–63.CrossRefGoogle ScholarPubMed
Di Chiara, G. (1999) Drug addiction as dopamine-dependent associative learning disorder. European Journal of Pharmacology 375(1–3):13–30.CrossRefGoogle ScholarPubMed
Di Chiara, G. & Imperato, A. (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences USA 85(14):5274–78.CrossRefGoogle ScholarPubMed
Kalivas, P. W. & Volkow, N. D. (2005) The neural basis of addiction: A pathology of motivation and choice. American Journal of Psychiatry 162(8):1403–13.CrossRefGoogle ScholarPubMed
Kelley, A. E. (2004a) Memory and addiction: Shared neural circuitry and molecular mechanisms. Neuron 44:161–79.CrossRefGoogle ScholarPubMed
Koob, G. F. & Le Moal, M. (1997) Drug abuse: Hedonic homeostatic dysregulation. Science 278(5335):52–58.CrossRefGoogle ScholarPubMed
Monterosso, J. R., Flannery, B. A., Pettinati, H. M., Oslin, D. W., Rukstalis, M., O'Brien, C. P. & Volpicelli, J. R. (2001) Predicting treatment response to naltrexone: The influence of craving and family history. American Journal on Addictions 10(3):258–68.CrossRefGoogle ScholarPubMed
Robbins, T. W. & Everitt, B. J. (1999) Drug addiction: Bad habits add up. Nature 398(6728):567–70.CrossRefGoogle ScholarPubMed
Robinson, T. E. & Berridge, K. C. (2000) The psychology and neurobiology of addiction: An incentive-sensitization view. Addiction 95(S2):S91–117.CrossRefGoogle ScholarPubMed
Rocha, B. A. (2003) Stimulant and reinforcing effects of cocaine in monoamine transporter knockout mice. European Journal of Pharmacology 479(1–3):107–15.CrossRefGoogle ScholarPubMed
Roesch, M. R., Takahashi, Y., Gugsa, N., Bissonette, G. B. & Schoenbaum, G. (2007) Previous cocaine exposure makes rats hypersensitive to both delay and reward magnitude. Journal of Neuroscience 27(1):245–50.CrossRefGoogle ScholarPubMed
Schoenbaum, G., Roesch, M. & Stalnaker, T. A. (2006a) Orbitofrontal cortex, decision making, and drug addiction. Trends in Neurosciences 29(2):116–24.CrossRefGoogle ScholarPubMed
Tanda, G., Pontieri, F. E. & Chiara, G. D. (1997) Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common µ1 opioid receptor mechanism. Science 276(5321):2048–50.CrossRefGoogle ScholarPubMed
Volkow, N. D. & Fowler, J. S. (2000) Addiction, a disease of compulsion and drive: Involvement of the orbitofrontal cortex. Cerebral Cortex 10(3):318–25.CrossRefGoogle ScholarPubMed
Wise, R. A. & Bozarth, M. A. (1987) A psychomotor stimulant theory of addiction. Psychological Review 94(4):469–92.CrossRefGoogle ScholarPubMed
Zack, M. & Poulos, C. X. (2004) Amphetamine primes motivation to gamble and gambling-related semantic networks in problem gamblers. Neuropsychopharmacology 29(1):195–207.CrossRefGoogle ScholarPubMed