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A wide-spectrum coordination model of schizophrenia

Published online by Cambridge University Press:  03 September 2003

Hendrik Pieter Barendregt
Hendrik Pieter Barendregt*
Affiliation:
Nijmeegse Instituut voor Informatica en Informatiekunde, 6500 GL Nijmegen, The Netherlands henk@cs.kun.nlhttp://www.cs.kun.nl/~henk
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Abstract

The target article presents a model for schizophrenia extending four levels of abstraction: molecules, cells, cognition, and syndrome. An important notion in the model is that of coordination, applicable to both the level of cells and of cognition. The molecular level provides an “implementation” of the coordination at the cellular level, which in turn underlies the coordination at the cognitive level, giving rise to the clinical symptoms.

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Article Commentary
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Behavioral and Brain Sciences , Volume 26 , Issue 1 , February 2003 , pp. 84 - 85
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Copyright © Cambridge University Press 2003

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