Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-14T09:09:31.287Z Has data issue: false hasContentIssue false
  • English
  • Français

Biotin studies in pigs

3. Biotin absorption and synthesis

Published online by Cambridge University Press:  09 March 2007

J. S. Kopinski ,
Jane Leibholz  and
W. L. Bryden
J. S. Kopinski
Affiliation:
Department of Animal Husbandry, University of Sydney, Camden, New South Wales 2570, Australia
Jane Leibholz
Affiliation:
Department of Animal Husbandry, University of Sydney, Camden, New South Wales 2570, Australia
W. L. Bryden
Affiliation:
Department of Animal Husbandry, University of Sydney, Camden, New South Wales 2570, Australia
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Eight pigs were given a semi-purified diet based on maize flour and casein containing 10 μg biotin/kg. The diet was given ad lib. with or without a supplement of 70 μg biotin/kg diet from 5 to 94 d of age. The flow of biotin in the stomach was similar to the biotin intake (13.5 and 112 μg/d) for the unsupplemented and biotin-supplemented pigs respectively. The flow of biotin through the small intestine decreased for the biotin-supplemented pigs from 39 μg/d in the first quarter of the small intestine to 7.9 μg/d in the last quarter. The flows of biotin in the caecum, large intestine and colon were similar for both the unsupplemented and biotin-supplemented pigs, with values of 17–54 μg/d, indicating the synthesis of biotin in the hind-gut.

Keywords

Biotin synthesisPig
Type
Vitamins
Information
British Journal of Nutrition , Volume 62 , Issue 3 , November 1989 , pp. 767 - 772
Copyright
Copyright © The Nutrition Society 1989

References

REFERENCES

Barth, C.A., Frigg, M. & Hagemeister, H. (1986). Biotin absorption from the hind gut of the pig. Journal of Animal Physiology and Animal Nutrition 55, 128–134.CrossRefGoogle Scholar
Berger, E., Long, E. & Semenz, A.G. (1972). The sodium activation of biotin absorption in hamster small intestine in vitro. Biochimica Biophysica Acta 255, 873–887.CrossRefGoogle ScholarPubMed
Christensen, K. (1980). Evaluation of the background for determination of vitamin requirements in pigs. Livestock Production Science 7, 569–590.CrossRefGoogle Scholar
Dreizen, S. & Hampton, J.K. (1969). Radioisotopic studies of the glandular contribution of selected B vitamins in saliva. Journal of Dental Research 48, 579–582.CrossRefGoogle ScholarPubMed
Ford, J.E., Scott, K.J., Sansom, B.F. & Taylor, P.J. (1975). Some observations on the possible nutritional significance of vitamin B12 and folate-binding proteins in milk. Absorption of [58Co]cyanocobalamin by suckling pigs. British Journal of Nutrition 34, 469–492.CrossRefGoogle Scholar
Frigg, M. (1976). Bio-availability of biotin in cereals. Poultry Science 55, 2310–2318.CrossRefGoogle Scholar
Henderickx, H.K., Teague, H.S., Redman, D.R. & Griffo, A.P. Jr (1964). Absorption of vitamin B12 from the colon of the pig. Journal of Animal Science 23, 1036–1038.CrossRefGoogle Scholar
Holdsworth, E.S. & Coates, M.E. (1961). The absorption of vitamin B12 in animals. II. The site of absorption of vitamin B12 and mode of action of intrinsic factor. Clinica Chimica Acta 6, 44–55.Google Scholar
Hood, R.L. (1977). The use of linear regression analysis in the isotope dilution assay of biotin. Analytical Biochemistry 79, 635–638.CrossRefGoogle ScholarPubMed
Kopinski, J.S., Leibholz, J., Bryden, W.L. & Fogarty, A.C. (1989). Biotin studies in pigs. 1. Biotin deficiency in the young pig. British Journal of Nutrition 62, 751–759.CrossRefGoogle ScholarPubMed
McCormick, D.B. & Wright, L.D. (1971). Metabolism of water-soluble vitamins. In Comprehensive Biochemistry, vol. 21, pp. 81–110 [Flarkin, M. and Stotz, E.H., editors]. Amsterdam: Elsevier Publishing Company.Google Scholar
Spencer, R.C. & Brody, K.R. (1964). Biotin transport of small intestine of rat, hamster and other species. American Journal of Physiology 206, 653–657.CrossRefGoogle ScholarPubMed
Steel, R.G.D. & Torrie, J.H. (1980). Principles and Procedures of Statistics, 2nd ed. New York: McGraw-Hill.Google Scholar
Tagwerker, F.J. (1978). Roche Information Service Bulletin no. 1675. Basle: Roche Products Ltd.Google Scholar
Vervaeke, I.J., Decuypere, J.A., Dierick, N.A. & Henderickx, H.K. (1979). Quantitative in vitro evaluation of the energy metabolism influenced by virginiamycin and spiramycin used as growth parameters in pig nutrition. Journal of Animal Science 49, 846–854.Google Scholar
Volker, L. & Smith, M.W. (1980). Current problems involving vitamins. Recent findings on the role of biotin in swine nutrition. In Proceedings of the Western Nutrition Conference, University of Saskatchewan, Saskatoon.Google Scholar