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Biotin studies in pigs

2. The biotin requirement of the growing pig

Published online by Cambridge University Press:  09 March 2007

J. S. Kopinski  and
Jane Leibholz
J. S. Kopinski
Affiliation:
Department of Animal Husbandry, University of Sydney, Camden, New South Wales 2570, Australia
Jane Leibholz
Affiliation:
Department of Animal Husbandry, University of Sydney, Camden, New South Wales 2570, Australia
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Abstract

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Twenty pigs weaned at 5 d were given pelleted diets based on maize flour and casein and supplemented with 0,50,100,150 or 200 μg biotin/kg diet. The performance of the pigs was not influenced by the biotin content of the diets. Typical biotin deficiency symptoms (foot lesions and skin pustules) were observed in pigs given the unsupplemented diet and the diet supplemented with 50 μg biotin/kg diet. Tissue biotin concentration plateaued when 100 μg biotin/kg was added to the diet. Faecal biotin excretion was independent of dietary biotin intake, but increased with age. Urine biotin excretion at 102 d was significantly lower for the unsupplemented pigs than for the pigs given various levels of dietary biotin supplements. A dietary requirement of biotin for young pigs between 50 and 100 μg/kg diet is suggested from the results of the present experiment.

Keywords

Biotin requirementPig
Type
Vitamins
Information
British Journal of Nutrition , Volume 62 , Issue 3 , November 1989 , pp. 761 - 766
Copyright
Copyright © The Nutrition Society 1989

References

REFERENCES

Agricultural Research Council (1981). Nutrient Requirement of Pigs. Slough: Commonwealth Agricultural Bureaux.Google Scholar
Brooks, P.H., Smith, D.A. & Irwin, V.C.R. (1977). Biotin supplementation of diets: the incidence of foot lesions and the reproductive performance of sows. Veterinary Record 101, 46–50.CrossRefGoogle ScholarPubMed
Cunha, T.J., Lindley, D.C. & Ensminger, M.E. (1946). Biotin deficiency syndrome in pigs fed desiccated egg white. Journal of Animal Science 5, 219–225.CrossRefGoogle Scholar
Hamilton, G.R., Veum, T.L., Jewell, D.E. & Siweck, J.A. (1983). The biotin status of weanling pigs fed semipurified diets as evaluated by plasma and hepatic parameters. International Journal of Vitamin and Nutrition Research 53, 44–50.Google ScholarPubMed
Hood, R.L. (1977). The use of linear regression analysis in the isotope dilution assay of biotin. Analytical Biochemistry 79, 635–638.CrossRefGoogle ScholarPubMed
Kopinski, J.S., Bryden, W.L. & Leibholz, J. (1986). Roche Information Service Bulletin no. 2022. Basle, Switzerland: Roche Products Ltd.Google Scholar
Kopinski, J.S., Leibholz, J., Bryden, W.L. & Fogarty, A.C. (1989). Biotin studies in pigs. 1. Biotin deficiency in the young pig. British Journal of Nutrition 62, 751–759.CrossRefGoogle ScholarPubMed
Lehrer, W.P., Wiese, A.C. & Moore, P.R. (1952). Biotin deficiency in suckling pigs. Journal of Nutrition 47, 203–212.CrossRefGoogle ScholarPubMed
National Research Council (1988). Nutrient Requirements of Domestic Animals, no. 2, Nutrient Requirements of Swine, 9th ed. Washington, DC: National Academy of Sciences.Google Scholar
Newport, M.J. (1981). A note on the effect of low levels of biotin in milk substitutes for neonatal pigs. Animal Production 33, 333–335.Google Scholar
Osuga, D.T. & Feeney, R.E. (1977). Egg proteins. In Food Proteins, pp. 209–266 [Whitaker, J.R. and Tannerbaum, S.R., editors]. Westport, Connecticut: AVI Publishing Company Inc.Google Scholar
Steel, R.G.D. & Torrie, J.H. (1980). Principles and Procedures of Statistics, 2nd ed. New York: McGraw-Hill.Google Scholar
Zahnley, J.C. (1974). Evidence that the two binding sites for trypsin on chicken ovoinhibitor are not equivalent. Journal of Biological Chemistry 249, 4282–4285.CrossRefGoogle Scholar