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Pseudogout of the Transverse Atlantal Ligament: An Unusual Cause of Cervical Myelopathy

Published online by Cambridge University Press:  16 February 2016

Donald E.G. Griesdale Jr.
Affiliation:
Division of Neurosurgery, Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver BCCanada
Mike Boyd
Affiliation:
Division of Neurosurgery, Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver BCCanada
Ramesh L. Sahjpaul*
Affiliation:
Division of Neurosurgery, Combined Neurosurgical and Orthopedic Spine Program, Vancouver General Hospital, University of British Columbia, Vancouver BCCanada
*
3878 W 18th Ave, Vancouver BC V6S 1B5, Canada.
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Abstract

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Background:

Calcium pyrophosphate dihydrate deposition in the cervical spine is infrequently symptomatic. This is especially true at the craniocervical junction and upper cervical spine.

Case Report:

A 70-year-old previously healthy woman presented with a progressive cervical myelopathy of four months duration.

Results:

Examination revealed sensorimotor findings consistent with an upper cervical myelopathy. Radiological studies (plain radiographs, computed tomography, and magnetic resonance imaging) revealed C1-2 instability, and a well-defined extradural 3cm x 1cm retro-odontoid mass causing spinal cord compression. Transoral resection of the mass was performed followed by posterior C1-2 stabilization. Histological examination of the mass confirmed calcium pyrophosphate dihydrate deposition. Follow-up examination showed marked clinical and radiological improvement.

Conclusion:

Although uncommon, calcium pyrophosphate dihydrate deposition disease should be considered in the differential diagnosis of extradural mass lesions in the region of the odontoid.

Type
Case Report
Copyright
Copyright © The Canadian Journal of Neurological 2004

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