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Response Recovery Cycles in the Visual Cortex and Superior Colliculus Following Conditioning ‘ON” and ‘OFF” Stimulation in the Rabbit

Published online by Cambridge University Press:  03 July 2018

Stéphane Molotchnikoff  and
Michel Dubuc
Stéphane Molotchnikoff*
Affiliation:
Département de Sciences biologiques, Université de Montréal, C.P. 6128, Montréal (Qué.), Canada, H3C 3J7
Michel Dubuc
Affiliation:
Département de Sciences biologiques, Université de Montréal, C.P. 6128, Montréal (Qué.), Canada, H3C 3J7
*
Département de Sciences biologiques, Université de Montréal C.P. 6128. Montréal, Canada H3C 3J7.
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Summary

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The responsiveness of the visual cortex (VC) and superior colliculus (SC) was simultaneously compared following conditioning “ON” or “OFF” stimulation, in the rabbit.

Average evoked responses were recorded simultaneously from the visual cortex and superior colliculus. “ON” or “OFF” steps constituted the conditioning stimuli whereas the test stimulus consisted of optic nerve stimulation. All evoked responses exhibited a reversal of their polarity when the electrode was moved in the dorsoventral direction (Negative-Positive in the SC, Positive-Negative in the VC). This assured the somato-dentritic origin of the potentials. The results showed that responsiveness in both structures was significantly higher following an “OFF” stimulus than after an “ON” step. Collicular responsiveness was higher than in the VC when the same conditioning stimulus was applied. The spatial distribution of the source of “OFF” responses was circumscribed to the ventral part of the superficial layer of the superior colliculus. These results suggest specific properties associated with the brightening and dimming systems.

Résumé

Résumé

Par la technique du double choc, le cycle de récupération post-réactionnelle (RPR) a été étudié simultanément au niveau du cortex visuel (CV) et au niveau du colliculus supérieur (CS), chez le lapin. Les chocs conditionnant étaient de deux types, soit la stimulation “ON”, soit la stimulation “OFF”. Les réponses tests ont été évoquées par une stimulation du nerf optique, court-circuit ant ainsi l’étape rétinienne. Toutes les réponses ont présenté une inversion de polarité dorsoventrale du CV et du CS, assurant ainsi une origine post-synaptique. Les résultats montrent que l’excitabilité post-réactionnelle est significativement plus élevée après une stimulation conditionnante “OFF” qu’après un conditionnement de type opposé, c’est-à-dire “ON”.

Pour un même type de stimulation conditionnante, la réactivité colliculaire est plus élevée que celle du cortex visuel. Au niveau du colliculus supérieur, les potentiels évoqués par la stimulation “OFF” présentent une distribution spatiale circonscrite à la portion ventrale des couches superficielles du CS. Cette étude permet d’associer des propriétés spécifiques aux systèmes “ON” et “OFF”.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 4 , Issue 1 , February 1977 , pp. 31 - 37
Copyright
Copyright © Canadian Neurological Sciences Federation 1977

References

Armington, J. C. (1974). The electroretinogram. Academic Press. N.Y., 317–320.Google Scholar
Berman, N., Cynader, M. (1972). Comparison of receptive field organization of the superior colliculus in Siamese and normal cats. Journal of Physiology, Lond. 224, 363–389.Google Scholar
Buser, P. (1955). Etude de l’activité électrique du lope optique des vertébrés inférieurs (I). Journal de Physiologie, Paris, 47, 737–768.Google Scholar
Buser, P. (1956). Etude de l’activité électrique du lobe optique des vertébrés inférieurs (II). Journal de Physiologie, Paris, 48, 49–71.Google Scholar
Creutzfeld, O. D., Kuhnt, U. (1973). Electrophysiology and topographical distribution of visual evoked potentials in animals. In: Handbook of Sensory Physiology Vol. VII/3A, Ed. Jung, , Berlin-Heidelberg. New York. 595–646.Google Scholar
Dubuc, M. (1976). Etude comparative des potentiels évoqués simultanément au collicule supérieur et au cortex visuel par le “ON” et le ‘OFF” d’un éclair lumineux chez le lapin. Thèse de Maîtrise, Université de Montréal.Google Scholar
Freund, H. J. (1972). Neuronal mechanisms of the lateral geniculate body. In: Handbook of Sensory Physiology Vol. VII/3B, Ed. Jung, R., Berlin-Heidelberg. New York, 177–246.Google Scholar
Goodale, M. A. (1973). Cortico-tectal and intertectal modulation of visual responses in the rat’s superior colliculus. Experimental Brain Research, 17, 75–86.Google Scholar
Grasset, P. P.,Dekeyser, P. L. (1955). Traité de Zoologie. T. 17, Masson, Paris, 1307–1314.Google Scholar
Jeannerod, M. (1974). Les deux mécanismes de la vision. La Recherche, 5, 23–32.Google Scholar
Jung, R. (1973). Visual perception and neurophysiology In: Handbook of Sensory Physiology. Vol. VII/3A, Ed. Jung, Berlin-Heidelberg. New York 1–152.Google Scholar
Landau, W. H. (1967). Evoked potentials. In: The Neurosciences. A Study Program. Ed. Quarton, , The Rockefeller University Press, New York, 469–482.Google Scholar
Lederman, R. J., Noell, W. K. (1968). Fast-fiber system of rabbit optic nerve. Vision Research, 8, 1385–1398.CrossRefGoogle ScholarPubMed
Lison, L. (1968). Statistique appliquée à la biologie expérimentale. Gauthier Villars, Paris, 207–210.Google Scholar
Magnussen, S. et Glad, A. (1975). Brightness and darkness enchancement during flicker: Perceptual correlates of neuronal B and D systems in human vision. Experimental Brain Research 22, 399–413.Google Scholar
Marty, R., Sherrer, J. (1964). Critères de maturation des systèmes afférents corticaux. Progress in Brain Research 4, 222–236.Google Scholar
Molotchnikoff, S., Dubuc, M., Brunette, J. R. (1975). Simultaneous recordings of visual cortex and superior colliculus field potentials in rabbit. Canadian Journal of Neurological Sciences, 2, 61–66.Google Scholar
Molotchnikoff, S., Dubuc, M., Brunette, J. R. (1976). Influence of the visual cortex upon visual evoked responses in the rabbit. Expérientia, 32, 72–73.Google Scholar
Morotomi, T., Kitajima, S. (1975). Enhancement of evoked responses to brief flashes and its correlation with “OFF” responses to pre-exposed light stimulation. Vision Research, 15, 272–276.Google Scholar
Muntz, W. R. A. (1962). Microelectrode recordings from the diencephalon of the frog (Rana pipiens). Journal of Neurophysiology, 25, 699–711.Google Scholar
Prince, J. H. (1964). The rabbit in eye research. Ed.: Prince Charles C., Thomas Sprinfield, 391.Google Scholar
Rodieck, R. W. (1973). The vertebrate retina. W. H. Freeman and Company, San Francisco, 560–590.Google Scholar
Sawyer, C. H., Everett, J. W. Green, J. D. (1954). The rabbit diencephalon in stereotaxic coordinates. Journal of comparative neurology 101, 801–824.CrossRefGoogle ScholarPubMed
Schaffer, K. P. (1970). Unit analysis and electrical stimulation of the optic tectum of rabbits and cats. Brain Behaviour and Evolution, 3, 222–240.Google Scholar
Schiller, P. N., Koerner, F. (1967). Discharge characteristics of single units in superior colliculus of the alert Rhesus Monkey. Journal of Neurophysiology, 31, 52–62.Google Scholar
Stériade, M. (1969). Physiologie des voies et des centres visuels. Masson, Paris, 54–109.Google Scholar
Sterling, P. (1971). Receptive field and synaptic organization of the superficial gray layer of the cat superior colliculus. Vision Research, Suppl. 3, 309–328.Google Scholar
Szentagothaï, J. (1973). Synaptology of the visual cortex. In: Handbook of Sensory physiology. Vol. VII/3B, Ed. Jung, R.. Berlin-Heidelberg, 270–324.Google Scholar
Tamai, M., Ogawa, I. (1972). Interaction between cortico-tectal and retino-tectal inputs as revealed by analysis of field potentials of the cat’s superior colliculus. Tohoku Journal of Experimental Medicine 107, 127–142.Google Scholar
Thompson, J. M., Woolsey, C. N., Talbot, S. A. (1950). Visual areas I and II of cerebral cortex of the rabbit. Journal of Neurophysiology, 13, 277–288.Google Scholar
Vanegas, H., Laufer, M., Amat, J. (1974). The optic tectum. I. General configuration and cytoarchitecture. Journal of Comparative Neurology, 154, 43–60.Google Scholar
Werblin, F., Dowling, J. E. (1969). Organization of the retina of the Mudpuppy Necturus Maculosus. II. Intracellular recordings. Journal of Neurophysiology, 32, 339–355.CrossRefGoogle Scholar
Wickelgren, B. G., Sterling, P. (1969). Influence of visual cortex on receptive fields in the superior colliculus of the Cat. Journal of Neurophysiology, 32, 16–23.Google Scholar