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5-HT1B/1D Receptors in Psychiatry and Neurology

Published online by Cambridge University Press:  07 November 2014

Mike Briley
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Abstract

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Type
Introduction
Information
CNS Spectrums , Volume 3 , Issue 8: Serotonin Subsystems , September 1998 , pp. 20
Copyright
Copyright © Cambridge University Press 1998

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References

REFERENCES

1.Zifa, E, Fillion, G. 5-Hydroxytryptamine receptors. Pharmacol Rev. 1992;44:402–458.Google Scholar
2.Weinshank, RL, Zgombick, JM, Macchi, MJ, Branchek, TA, Hartig, PR. Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1Dα and 5-HT1Dβ. Proc Natl Acad Sci USA. 1992;89:3630–3634.Google Scholar
3.Hartig, PR, Hoyer, D, Humphrey, PPA, Martin, GAlignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes. Trends Pharmacol Sci. 1996;17:103–105.Google Scholar
4.Metcalf, MA, McGuffin, RW, Hamblin, MW. Conversion of the human 5-HT1Dβ serotonin receptor to the rat 5-HT1B ligand-binding phenotype by Thr (355) Asn site directed mutagenesis. Biochem Pharmacol. 1992;44:1917–1920.Google Scholar
5.Oksenberg, J, Marsters, SA, O'Dowd, BF, et al.A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors. Nature. 1992;360:161–163.CrossRefGoogle ScholarPubMed
6.Parker, EM, Grisel, DA, Iben, LG, Shapiro, RA. A single amino acid difference accounts for the pharmacological distinctions between the rat and human 5-hydroxytryptamine (1B) receptors. J Neurochem. 1993;60:380–383.Google Scholar