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Calming the Bipolar Storm: Treating Acute Mania and Mixed Episodes in Patients with Bipolar Disorder

Published online by Cambridge University Press:  07 November 2014

John M. Zajecka
John M. Zajecka*
Affiliation:
Dr. Zajecka is associate professor of psychiatry and clinical director of the Treatment Research Center in the Department of Psychiatry at Rush University Medical Center in Chicago, Illinois, and Rush North Shore Medical Center in Skokie, Illinois. He is a consultant to and on the advisory boards of Abbott, Bristol-Myers Squibb, Eli Lilly, and Wyeth; is on the speaker&s bureaus of Abbott, AstraZeneca, Bristol-Myers Squibb, Cyberonics, Eli Lilly, GlaxoSmithKline, Pfizer, and Wyeth; and receives grant/research support from AstraZeneca, Bristol-Myers Squibb, Forest, Novartis, Ortho-McNeil, and Somaxon.
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Abstract

Bipolar disorder is a seriously debilitating psychiatric disorder that greatly affects patients and their loved ones. Although bipolar disorder is one of the most frequently occurring mental disorders worldwide, many patients, particularly those with mixed mania, remain misdiagnosed. Compared to pure mania, mixed episodes of bipolar disorder present with symptoms that can be more challenging to treat. However, proper diagnosis and early treatment can usually alter the course of the illness, and remission is certainly possible.

This expert roundtable supplement reviews the differences between acute manic and mixed episodes in patients with bipolar disorder, explains proper dosing and the advantages of different dosage formulations, and identifies the rationale for monotherapy and combination therapy in these patient populations. The aim is to educate clinicians about ways to diagnose and treat the mood state aggressively and safely, especially in light of the many new treatment options available.

Type
Research Article
Information
CNS Spectrums , Volume 11 , Issue S13 , November 2006 , pp. 1 - 16
Copyright
Copyright © Cambridge University Press 2007

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