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Metabolic and Endocrine Disturbances in Psychiatric Disorders: A Multidisciplinary Approach to Appropriate Atypical Antipsychotic Utilization

Published online by Cambridge University Press:  07 November 2014

Prakash S. Masand ,
Larry Culpepper ,
David Henderson ,
Scott Lee ,
Kimberly Littrell ,
John W. Newcomer  and
Natalie Rasgon
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Abstract

Patients with psychiatric disorders have an increased rate of cardiovascular morbidity and mortality compared with the general population. Metabolic issues such as weight gain, dyslipidemia, diabetes mellitus, diabetic ketoacidosis, and pancreatitis have been reported with the use of antipsychotic agents. Although atypical antipsychotics have not been linked directly to the development of metabolic syndrome, these medications have been shown to increase risk factors that can lead to metabolic and endocrine disturbances. Therefore, clinicians should provide ongoing monitoring for patients who are being treated for psychiatric disorders with these agents. According to the 2004 Consensus Report on Antipsychotics, screening measures should include baseline and follow-up monitoring of personal/family histories, weight (body mass index), waist circumference, blood pressure, fasting plasma glucose, and fasting lipid profile.

Type
Clinical Information Monograph
Information
CNS Spectrums , Volume 10 , Issue 10 , October 2005 , pp. 819a - 819l
Copyright
Copyright © Cambridge University Press 2005

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