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Abnormal Reactions to Horse Serum in the Serum Treatment of Cerebrospinal Fever

Published online by Cambridge University Press:  15 May 2009

J. R. Currie
Affiliation:
Assistant Physician, Belvidere Fever Hospital, Glasgow.
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The following general statements are applicable to the 50 cases of cerebrospinal fever which have been under notice here.

The total volume of serum given did not affect the frequency of abnormal reactions.

The total number of injections of serum, in certain cases, may have been a factor in inducding abnormal reactions.

The interval of time between the injections concerned was the primary influence in determining abnormal reactions.

It was not apparent that a preceding normal reaction predisposed to a subsequent abnormal reaction.

It was not apparent that a large administration of serum within the latent period predisposed to a subsequent abnormal reaction.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1908

References

Currie, (I. 1907). On the Supersensitation of persons suffering from Diphtheria by repeated injections of Horse Serum. Journ. of Hygiene, vol. VII. pp. 40, 57.Google Scholar
Friedemann, (1907). Ueber passive Ueberempfindlichkeit. Centralbl. für Bakt. Ref. vol. XLI. p. 584, from München. med. Wochenschr. 1907, p. 2414.Google Scholar
Goodall, (VII. 1907). On the Supersensitation of persons by Horse Serum. Journ. of Hygiene, vol. VII. pp. 607, 618.Google Scholar
Goodman, (VI. 1907). Observations on Natural Immunity and Susceptibility to Diphtheria Toxin. Journ. of Inf. Dis., vol. IV. No. 3, pp. 509, 536.CrossRefGoogle Scholar
Lewis, (1908). The induced susceptibility of the Guinea-pig to the toxic action of the blood serum of the Horse. Centralbl. für Bakt. Ref. vol. XLI. p. 584. from Journ. of Exp. Med. 1908, p. 1.Google Scholar
Nicolle, and Abt (II. 1908). Une conception générale des anticorps et de leurs effets. Les anticorps des albuminoïdes et des cellules. Ann. Inst. Pasteur, vol. XXII. p. 133.Google Scholar
Nicolle, and Pozerski, (I. 1908). Une conception générale des anticorps et de leurs effets. Les anticorps des toxines solubles. Ann. Inst. Pasteur, vol. XXII. p. 47.Google Scholar
Otto, . Das Theobald Smithsche Phänomen der Serum-Ueberempfindlichkeit (Reprint). von Leuthold Festschrift, vol. I. pp. 15, 19.Google Scholar
Otto, (1907). Zur Frage der Serum-Ueberempfindlichkeit (Reprint). München. med. Wochenschr. No. 34, pp. 1, 7, 10.Google Scholar
von Pirquet, and Schick, (1905). Die Serumkrankheit. Franz Deuticke, Leipzig and Wien, pp. 84, 120.Google Scholar
Rosenau, and Anderson, (IV. 1906). A Study of the Cause of Sudden Death following the injection of Horse Serum. Bull. No. 29 Hyg. Lab. U.S. Pub. Health and Mar. Hosp. Serv., Wash. pp. 54, 73, 91.Google Scholar
Rosenau, and Anderson, (VII. 1906). A new toxic action of Horse Serum. Journ. of Med. Research, vol. XV. p. 194.Google Scholar
Rosenau, and Anderson, (VII. 1907). Further studies upon Hypersusceptibility and Immunity. Journ. of Med. Research, vol. XVI. No. 3, pp. 382, 400, 402.Google Scholar
Rosenau, and Anderson, (XI. 1907). The Specific Nature of Anaphylaxis. Journ. of Inf. Dis. vol. IV, No. 4, p. 552.CrossRefGoogle Scholar
Vaughan, and Wheeler, (VI. 1907). The effects of Egg White and its Split Products on Animals: a study of Susceptibility and Immunity. Journ. of Inf. Dis. vol. IV. No. 3, pp. 476, 492.CrossRefGoogle Scholar
Wassermann, (1907). Ueber die bisherigen Erfahrungen mit dem Meningococcen-Heilserum bei Genickstarrekranken. Deutsche med. Wochenschr. Jg. XXXIII. S. 1586.Google Scholar
Wolff, (1904). Ueber Grundgesetze der Immunität. Centralbl. für Bakt. Orig. vol. XXXVII. p. 397.Google Scholar