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An outbreak of aseptic meningitis associated with Coxsackie B5 and A9 viruses in Northern Japan, 1961. Virological and serological studies

Published online by Cambridge University Press:  15 May 2009

Yorio Hinuma ,
Yoshimichi Murai ,
Minoru Fukuda ,
Yoshio Numazaki ,
Nakao Ishida  and
Tooru Nakao
Yorio Hinuma
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Yoshimichi Murai
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Minoru Fukuda
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Yoshio Numazaki
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Nakao Ishida
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Tooru Nakao
Affiliation:
Paediatric Clinic, Aomori Prefectural Central Hospital, Aomori, Japan
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Virological and serological studies on an outbreak of aseptic meningitis in association with Coxsackie B5 virus, and Coxsackie A9 virus to a lesser extent, are reported. Coxsackie B5 virus was isolated from spinal fluids of 60 patients and Coxsackie A 9 virus from one spinal fluid. Fifty Coxsackie B 5 and 13 Coxsackie A 9 viruses were recovered from patients' faeces. The evidence that the epidemic was caused by these viruses was confirmed by determination of neutralizing antibody in paired sera.

The plaque variants of Coxsackie B5 virus isolated from the faecal specimens and the poor antibody response in Coxsackie A 9 infection were reported as points of virological and serological interest.

Type
Research Article
Information
Journal of Hygiene , Volume 62 , Issue 2 , June 1964 , pp. 159 - 170
Copyright
Copyright © Cambridge University Press 1964

References

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