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Aspects of influenza C virus replication

Published online by Cambridge University Press:  15 May 2009

Grizel R. Barclay
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham
Lesley K. Leader-Williams
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham
T. H. Flewett
Affiliation:
Regional Virus Laboratory, East Birmingham Hospital, Birmingham
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Summary

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Influenza C virus antigen could be detected by immunofluorescence in chick amniotic epithelium 4 hr. after inoculation with undiluted amniotic fluid. Antigen could be detected in the nucleus of rhesus monkey kidney tissue cultures 10 hr. after infection. Only cytoplasmic fluorescence was observed 17–21 hr. after infection.

The pattern of replication was similar to that reported for group I myxoviruses, indicating that the virus is correctly classified as an influenza virus.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1971

References

REFERENCES

Breitenfeld, P. M. & Schäfer, W. (1957). The formation of fowl plague virus antigens in infected cells, as studied with fluorescent antibodies. Virology 4, 328.CrossRefGoogle ScholarPubMed
Francis, T. Jr., Quilligan, J. J. Jr. & Minuse, E. (1950). Identification of another epidemic respiratory disease. Science, New York 112, 495.CrossRefGoogle ScholarPubMed
Franklin, R. M. (1958). The synthesis of fowl plague virus products in a proflavine-inhibited tissue culture system. Virology 6, 525.CrossRefGoogle Scholar
Lief, F. S. & Henle, W. (1956). Studies on the soluble antigen of influenza virus. Virology 2, 753.CrossRefGoogle Scholar
Lief, F. S. & Henle, W. (1959). Methods and procedures for use of complement-fixation technique in type- and strain-specific diagnosis of influenza. Bulletin of the World Health Organisation 20, 411.Google Scholar
Lui, Ch'ien (1955). Studies on influenza infection in ferrets by means of fluorescein labelled antibody. II. The role of ‘soluble antigen’ in nuclear fluorescence and cross reactions. Journal of Experimental Medicine 101, 677.Google Scholar
Minuse, E., Quilligan, J. J. Jr. & Francis, T. Jr. (1954). Type C influenza virus. 1. Studies of the virus and its distribution. Journal of Laboratory and Clinical Medicine 43, 31.Google ScholarPubMed
Nelson, M. & Lewis, F. A. (1958). A relationship between swine and Asian strains of influenza A virus. Australian Journal of Experimental Biology and Medical Science 36, 505.CrossRefGoogle Scholar
Quilligan, J. J. Jr., Minuse, E. & Francis, T. Jr. (1951). Further observations on the JJ and 1233 influenza viruses. Federation Proceedings, Federation of American Societies for Experimental Biology 10, 416.Google Scholar
Taylor, R. M. (1949). Studies on survival of influenza virus between epidemics and antigenic variants of the virus. American Journal of Public Health 39, 171.CrossRefGoogle ScholarPubMed
Traver, M. I., Northrop, R. L. & Walker, D. L. (1960). Site of intracellular antigen production of myxoviruses. Proceedings of the Society for Experimental Biology and Medicine 104, 268.CrossRefGoogle ScholarPubMed
Watson, B. K. & Coons, A. H. (1954). Studies of influenza virus infection in the chick embryo using fluorescent antibody. Journal of Experimental Medicine 99, 419.CrossRefGoogle ScholarPubMed
Wheelock, E. F. & Tamm, I. (1959). Mitosis and division in Hela cells infected with influenza or Newcastle disease virus. Virology 8, 532.CrossRefGoogle ScholarPubMed