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Comparison of oral sucrose and glucose electrolyte solutions in the out-patient management of acute gastroenteritis in infancy

Published online by Cambridge University Press:  15 May 2009

P. Hutchins ,
T. H. J. Matthews ,
J. E. Manly ,
B. Lawrie  and
J. A. Walker-smith
P. Hutchins
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
T. H. J. Matthews
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
J. E. Manly
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
B. Lawrie
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
J. A. Walker-smith*
Affiliation:
Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS
*
*Queen Elizabeth Hospital for Children, Hackney Road, London E2 8PS.
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Summary

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Seventy-three children under the age of 18 months presenting with acute gastroenteritis were given an electrolyte mixture with added sucrose or glucose in a randomized double-blind trial. The time taken to recovery in those successfully treated as out-patients was identical. However, of the 34 who received glucose, 11 (32%) required admission compared with 7 (18%) of the 39 who received sucrose. There was a wide range of osmolality of the made-up feeds, indicating inaccuracy in diluting the solutions as prescribed, but this did not in general correlate with need for admission.

Sucrose-electrolyte solution is at least as effective as a glucose-electrolyte solution for the out-patient management of acute gastroenteritis in infancy. The cheapness and easy availability of sucrose commends its use in developed and developing countries.

Type
Research Article
Information
Journal of Hygiene , Volume 82 , Issue 1 , February 1979 , pp. 15 - 19
Copyright
Copyright © Cambridge University Press 1979

References

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