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The History of Six Old Cultures of Mycobactebium Tuberculosis

Published online by Cambridge University Press:  15 May 2009

A. Stanley Griffith
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Instances are recorded in the literature of mammalian -tubercle bacilli having lost their virulence completely during long cultivation on artificial media. In a paper published in 1925 I gave an account of the results of investigating two such strains which had been deposited in the National Collection of Type Cultures by Dr Nathan Raw. These strains were stated by Dr Raw to be lineal descendants of strains which had been given to him in 1906, one (human) by Prof. R. Koch, who had isolated it from the sputum of a case of human pulmonary tuberculosis, the other (bovine) by Prof. A. Calmette, who had obtained it from a mesenteric gland of a cow.

Type
Research Article
Information
Journal of Hygiene , Volume 41 , Issue 5-6 , December 1941 , pp. 530 - 542
Copyright
Copyright © Cambridge University Press 1941

References

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