Hostname: page-component-cd9895bd7-hc48f Total loading time: 0 Render date: 2024-12-28T00:34:47.541Z Has data issue: false hasContentIssue false

Breath interval as a continuous measure of opioid effects of intravenous fentanyl and alfentanil

Published online by Cambridge University Press:  11 July 2005

J. A. Smart
Affiliation:
University Department of Anaesthesia, Glenfield Hospital and Leicester Royal Infirmary, Leicester, UK
E. J. Pallett
Affiliation:
University Department of Anaesthesia, Glenfield Hospital and Leicester Royal Infirmary, Leicester, UK
David J. R. Duthie
Affiliation:
University Department of Anaesthesia, Glenfield Hospital and Leicester Royal Infirmary, Leicester, UK
Get access

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Correspondence
Copyright
© 2003 European Society of Anaesthesiology

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Smart JA, Pallett EJ, Duthie DJR. Breath interval as a measure of dynamic opioid effect. Br J Anaesth 2000; 84: 735738.Google Scholar
Goodman NW, Vanner RG, Wade JA. Effects of incremental alfentanil and propofol on the breathing of anaesthetised patients. Br J Anaesth 1989; 65: 548553.Google Scholar
Holford N. MKMODEL, 5th edn. Cambridge, UK: Biosoft, 1994.
Cheng H, Gillespie WR, Jusko WJ. Mean Residence Time concepts for non-linear pharmacokinetic systems. Biopharmaceut Drug Depos 1994; 15: 627641.Google Scholar
Ebling WF, Lee EN, Stanski DR. Understanding pharmacokinetics and pharmacodynamics through computer simulation: 1. The comparative clinical profiles of fentanyl and alfentanil. Anesthesiology 1990; 72: 650658.Google Scholar
Shafer SL, Varvel JR. Pharmacokinetics, pharmacodynamics and rational opioid selection. Anesthesiology 1991; 74: 5363.Google Scholar