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Increasing the injection volume by dilution improves the onset of motor blockade, but not sensory blockade of ropivacaine for brachial plexus block

Published online by Cambridge University Press:  02 June 2005

H. Krenn
Affiliation:
Department of Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria
E. Deusch
Affiliation:
Department of Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria Department of Anaesthesia and Critical Care, General Hospital, Vienna, Austria
B. Balogh
Affiliation:
Ludwig Boltzmann Institute for Quality Assurance in Plastic and Reconstructive Surgery, Innsbruck, Austria Department of Plastic and Reconstructive Surgery, City Hospital, Lainz, Vienna, Austria
H. Jellinek
Affiliation:
Department of Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria
W. Oczenski
Affiliation:
Department of Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria
E. Plainer-Zöchling
Affiliation:
Department of Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria
R. D. Fitzgerald
Affiliation:
Department of Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria Ludwig Boltzmann Institute for Economy in Anaesthesia and Critical Care, City Hospital, Lainz, Vienna, Austria
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Summary

Background and objective: Ropivacaine used for axillary plexus block provides effective motor and sensory blockade. Varying clinical dosage recommendations exist. Increasing the dosage by increasing the concentration showed no improvement in onset. We compared the behaviour of a constant dose of ropivacaine 150 mg diluted in a 30, 40 or 60 mL injection volume for axillary (brachial) plexus block.

Methods: A prospective, randomized, observer-blinded study on patients undergoing elective hand surgery was conducted in a community hospital. Three groups of patients with a constant dose of ropivacaine 150 mg, diluted in 30, 40 or 60 mL NaCl 0.9%, for axillary plexus blockade were compared for onset times of motor and sensory block onset by assessing muscle strength, two-point discrimination and constant-touch sensation.

Results: Increasing the injection volume of ropivacaine 150 mg to 60 mL led to a faster onset of motor block, but not of sensory block, in axillary plexus block, compared with 30 or 40 mL volumes of injection.

Conclusions: The data show that the onset of motor, but not of sensory block, is accelerated by increasing the injection volume to 60 mL using ropivacaine 150 mg for axillary plexus block. This may be useful for a more rapid determination of whether the brachial plexus block is effective. However, when performing surgery in the area of the block, sensory block onset seems more important.

Type
Original Article
Copyright
© 2003 European Society of Anaesthesiology

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References

Hickey R, Hoffman J, Ramamurthy S. A comparison of ropivacaine 0.5% and bupivacaine 0.5% for brachial plexus block. Anesthesiology 1991; 74: 639642.Google Scholar
Hickey R, Candido KD, Ramamurthy S, et al. Brachial plexus block with a new local anaesthetic: 0.5 per cent Ropivacaine. Can J Anaesth 1990; 37: 732738.Google Scholar
Casati A, Leoni A, Aldegheri G, Berti M, Torri G, Fanelli G. A double blind study of axillary brachial plexus block by 0.75% ropivacaine or 2% mepivacaine. Eur J Anaesthesiol 1998; 15: 549552.Google Scholar
Vainionpää VA, Haavisto ET, Huha TM, et al. A clinical and pharmacokinetic comparison of ropivacaine and bupivacaine in axillary plexus block. Anesth Analg 1995; 81: 534538.Google Scholar
Raeder JC, Drøsdahl S, Klaastad Ø, et al. Axillary brachial plexus block with ropivacaine 7.5 mg/ml. A comparative study with bupivacaine 5 mg/ml. Acta Anaesth Scand 1999; 43: 794798.Google Scholar
Hickey R, Rowley CL, Candido KD, Hoffman J, Ramamurthy S, Winnie AP. A comparative study of 0.25% ropivacaine and 0.25% bupivacaine for brachial plexus block. Anesth Analg 1992; 75: 602606.Google Scholar
Klein SM, Greengrass RA, Steele SM, et al. A comparison of 0.5% bupivacaine, 0.5% ropivacaine and 0.75% ropivacaine for interscalene brachial plexus block. Anesth Analg 1998; 87: 13161319.Google Scholar
Bertini L, Tagariello V, Mancini S, et al. 0.75% and 0.5% ropivacaine for axillary brachial plexus block: a clinical comparison with 0.5% bupivacaine. Reg Anesth Pain Med 1999; 24: 514518.Google Scholar
Winnie AP, Ramamurthy S, Durrani Z, Radonjic R. Interscalene cervical plexus block: a single-injection technique. Anesth Analg 1975; 54: 370375.Google Scholar
Mannerfelt L. Motor function testing. In: Omer GE, Spinner M, eds. Management of Peripheral Nerve Problems. Philadelphia, USA: W. B. Saunders, 1980: 1629.
Lee Dellon A. Sensibility testing. In: Gelberman RH, ed. Operative Nerve Repair and Reconstruction. Philadelphia, USA: Lippincott, 1991: 135158.
Bell-Krotoski JA. Sensibility testing: current concepts. In: Hunter JH, Mackin EJ, Callahan AD, eds. Rehabilitation of the Hand: Surgery and Therapy, 4th edn. St Louis, USA: C. V. Mosby, 1995: 109127.
Kampe S, Weigand C, Kaufmann J, Klimek M, Konig DP, Lynch J. Postoperative analgesia with no motor block by continuous epidural infusion of ropivacaine 0.1% and sufentanil after total hip replacement. Anesth Analg 1999; 89: 395398.Google Scholar
Thompson GE, Brown DL, Carpenter RL. An initial study of ropivacaine for epidural anesthesia. Anesth Analg 1989; 68: S290.Google Scholar
Concepcion M, Arthur GR, Steele SM, Bader AM, Covino BG. A new local anaesthetic, ropivacaine. Its epidural effects in humans. Anaesth Analg 1990; 70: 8085.Google Scholar
Rosenberg PH, Heinonen E. Differential sensitivity of A and C nerve fibres to long-acting amide local anaesthetics. Br J Anaesth 1983; 55: 163167.Google Scholar
Bader AM, Datta S, Flanagan H, Covino BG. Comparison of bupivacaine – and ropivacaine induced conduction blockade in the isolated rabbit vagus nerve. Anesth Analg 1989; 68: 724727.Google Scholar
Rosenberg PH, Kyttä J, Alila A. Absorption of bupivacaine, etidocaine, lignocaine and ropivacaine into n-heptane, rat sciatic nerve and human extradural and subcutaneous fat. Br J Anaesth 1986; 58: 310314.Google Scholar
Vester-Andersen T, Christiansen C, Sorensen M, Kaalund-Jorgensen HO, Sangbjerg P. Perivascular axillary block II: Influence of injected volume of local anaesthetic on neural blockade. Acta Anaesthesiol Scand 1983; 27: 9598.Google Scholar
Winnie AP, Radonjic R, Akkineni SR, Durrani Z. Factors influencing distribution of local anesthetic injected into the brachial plexus sheath. Anesth Analg 1979; 58: 225234.Google Scholar
De Jong RH. Axillary block of the brachial plexus. Anesthesiology 1961; 22: 215225.Google Scholar
Thompson GE, Rorie DK. Functional anatomy of the brachial plexus sheaths. Anesthesiology 1983; 59: 117122.Google Scholar
Partridge BL, Katz J, Benirschke K. Functional anatomy of the brachial plexus sheath: implications for anesthesia. Anesthesiology 1987; 66: 743747.Google Scholar
Morrrison LMM, Emanuelsson BM, McClure JH, et al. Efficacy and kinetics of extradural ropivacaine: comparison with bupivacaine. Br J Anaesth 1994; 72: 164169.Google Scholar