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El polimorfismo TaqIA asociado al gen del receptor D2 de dopamina está relacionado con una atención más baja y menos control inhibitorio en los pacientes alcohólicos

Published online by Cambridge University Press:  12 May 2020

R. Rodríguez-Jiménez ,
C. Ávila ,
G. Ponce ,
M. I. Ibáñez ,
G. Rubio ,
M. A. Jiménez-Arriero ,
I. Ampuero ,
J. A. Ramos ,
J. Hoenicka  and
T. Palomo
R. Rodríguez-Jiménez
Affiliation:
Unidad de Conductas Adictivas (UCA), Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Avda. de Córdoba s/n, 28041Madrid, España
C. Ávila
Affiliation:
Dpto. Psicología Básica, Clínica y Psicobiología, Universitat Jaime I, Castelló, España
G. Ponce
Affiliation:
Unidad de Conductas Adictivas (UCA), Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Avda. de Córdoba s/n, 28041Madrid, España
M. I. Ibáñez
Affiliation:
Dpto. Psicología Básica, Clínica y Psicobiología, Universitat Jaime I, Castelló, España
G. Rubio
Affiliation:
Servicios de Salud Mental, Retiro, Madrid, España
M. A. Jiménez-Arriero
Affiliation:
Unidad de Conductas Adictivas (UCA), Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Avda. de Córdoba s/n, 28041Madrid, España
I. Ampuero
Affiliation:
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
J. A. Ramos
Affiliation:
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
J. Hoenicka
Affiliation:
Unidad de Conductas Adictivas (UCA), Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Avda. de Córdoba s/n, 28041Madrid, España
T. Palomo
Affiliation:
Unidad de Conductas Adictivas (UCA), Servicio de Psiquiatría, Hospital Universitario 12 de Octubre, Avda. de Córdoba s/n, 28041Madrid, España
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Resumen

El polimorfismo TaqIA vinculado al gen del receptor D2 de dopamina se ha asociado con el alcoholismo. El propósito de este trabajo es estudiar la atención y el control inhibitorio mediante el test de ejecución continua y la tarea de detención en una muestra de 50 pacientes varones alcohólicos españoles divididos en dos grupos segύn la presencia del alelo TaqIA1 en su genotipo. Nuestros resultados muestran que los alcoholicos portadores del alelo TaqIA1 presentan atención sostenida más baja y menos control inhibitorio que los pacientes sin ese alelo.

Keywords

AlcoholismoPolimorfismo TaqIATest de ejecución continuaTarea de detenciónAtenciónControl Inhibitorio
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 13 , Issue 5 , June 2006 , pp. 253 - 256
Copyright
Copyright © European Psychiatric Association 2006

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