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Virus de la enfermedad de Borna y psiquiatría

Published online by Cambridge University Press:  12 May 2020

O. Taieb ,
J. M. Baleyte ,
P. Mazet  and
A. M. Fillet
O. Taieb
Affiliation:
Departamento de Virología, CERVI, 47-83 Boulevard de I'Hôpital, 75013París, Francia Departamento de Psiquiatría del Niño y del Adolescente, Grupo Hospitalario Pitié-Salpêtrière, 47-83 Boulevard de I'Hôpital, 75013París, Francia
J. M. Baleyte
Affiliation:
Departamento de Psiquiatría del Niño y del Adolescente, Grupo Hospitalario Pitié-Salpêtrière, 47-83 Boulevard de I'Hôpital, 75013París, Francia
P. Mazet
Affiliation:
Departamento de Psiquiatría del Niño y del Adolescente, Grupo Hospitalario Pitié-Salpêtrière, 47-83 Boulevard de I'Hôpital, 75013París, Francia
A. M. Fillet
Affiliation:
Departamento de Virología, CERVI, 47-83 Boulevard de I'Hôpital, 75013París, Francia
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Resumen

El virus de la enfermedad de Borna (VEB), un virus neurotrópico no citolítico con RNA “antisense” encapsulado no segmentado con una amplia distribución geográfica, infecta a varias especies de animales vertebrados y causa una enfermedad del sistema nervioso central (SNC) con mediación inmune y diversas manifestaciones, dependiendo tanto del huésped como de factores víricos. En las infecciones animales, el VEB puede persistir en el SNC e inducir alteraciones en las funciones de las células cerebrales, anomalías neuroevolutivas y perturbaciones del comportamiento. Algunos estudios serológicos y moleculares han propuesto una asociación entre el VEB y los trastornos psiquiátricos (esencialmente, la esquizofrenia y los trastornos afectivos), pero se requieren más investigaciones para establecer la posible contribución de este virus a la patogenésis de estos trastornos.

Keywords

autismotrastorno bipolarvirus de la enfermedad de Bornahipótesis neuroevolutivaesquizofrenia
Type
Revisión
Information
European Psychiatry (Ed. Española) , Volume 8 , Issue 4 , May 2001 , pp. 215 - 223
Copyright
Copyright © European Psychiatric Association 2001

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References

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