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Differences in interleukins’ patterns between dysthymia and major depression

Published online by Cambridge University Press:  16 April 2020

J. Schlatter ,
F. Ortuño  and
S. Cervera-Enguix
J. Schlatter*
Affiliation:
Department of Psychiatry and Medical Psychology, University Clinic, University of Navarra, 31080-Pamplona, Spain
F. Ortuño
Affiliation:
Department of Psychiatry and Medical Psychology, University Clinic, University of Navarra, 31080-Pamplona, Spain
S. Cervera-Enguix
Affiliation:
Department of Psychiatry and Medical Psychology, University Clinic, University of Navarra, 31080-Pamplona, Spain
*
*Correspondence and reprints. E-mail address:schlatter@unav.es (J. Schlatter).
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Summary

We assessed whether cytokine production–interleukin (IL)-1β, IL-6 and tumour necrosis factor-α (TNFα)–is affected in depressed patients, dysthymia (Dt) and major depression (MD), and its association with various parameters of severity and clinical course. We found a possible different pattern of interleukin production between Dt and MD.

Keywords

interleukin-1βinterleukin-6cytokinedysthymiamajor depressionmonocyte
Type
Short communication
Information
European Psychiatry , Volume 16 , Issue 5 , August 2001 , pp. 317 - 319
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2001

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References

Anisman, HRavindran, AVGriffiths, JMerali, Z.IL-1ß production in Dysthymia before and after pharmacotherapy. Biol Psychiatry 1999; 46: 1649–55.CrossRefGoogle Scholar
Anisman, HRavindran, AVGriffiths, JMerali, Z.Endocrine and cytokine correlates of major depression and dysthymia with typical or atypical features. Mol Psychiat 1999; 4: 182–8.CrossRefGoogle ScholarPubMed
Griffiths, JRavindran, AVMerali, ZAnisman, H.Immune and behavioural correlates of typical and atypical depression. Soc Neurosci Abst 1996; 22: 1350.Google Scholar
Hamilton, M.The assessment of anxiety states by rating. Br J Med Psychol 1959; 32: 50–5.CrossRefGoogle ScholarPubMed
Hamilton, M.Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6: 278–96.CrossRefGoogle ScholarPubMed
Kronfol, ZRemick, DG.Cytokines and the brain: implications for clinical psychiatry. Am J Psychiatry 2000; 157: 683–94.CrossRefGoogle ScholarPubMed
Leonard, BE.Peripheral markers of depression. Current Opin Psychiatry 2000; 13: 61–8.CrossRefGoogle Scholar
Maes, MBosmans, EMeltzer, HYScharpe, SSuy, E.Interleukin-1ß: a putative mediator of HPA axis hyperactivity in major depression?. Am J Psychiatry 1993; 150: 1189–93.Google Scholar
Maes, MSmith, RScharpe, S.The monocyte-T-lymphocyte hypothesis of major depression. Psychoneuroendocrinology 1995; 2: 111–6.CrossRefGoogle Scholar
Maes, M.Psychological stress, cytokines and the inflammatory response system. Current Opin Psychiatry 1999; 12: 695–700.CrossRefGoogle Scholar
Natelson, BHDenny, TZhou, XDLaManca, JJOttenweller, JETiersky, L., et al. Is depression associated with immune activation?. J Affect Disord 1999; 53: 179–84.CrossRefGoogle ScholarPubMed
Rothermundt, MArolt, VPeters, MGutbrodt, HFenker, JKersting, A., et al. Inflammatory markers in major depression and melancholia. J Affect Disord 2001; 63: 93–102.CrossRefGoogle ScholarPubMed
Weizman, RLaor, NPodliszewski, ENotti, IDjaldetti, MBessler, H.Cytokine production in major depressed patients before and after clomipramine treatment. Biol Psychiatry 1994; 35: 42–7.CrossRefGoogle ScholarPubMed
Xia, ZDePierre, JWNassberger, L.Tricyclic antidepressants inhibit IL-6, IL-1ß and TNFα release in human blood monocytes and IL-2 and interferon-γ in T cells. Immunopharmacology 1999; 34: 27–37.CrossRefGoogle Scholar
Zorrilla, EPRedei, EDeRubeis, R.J.Reduced cytokine levels and T-cell function in healthy males: relation to individual differences in subclinical anxiety. Brain Behav Immun 1994; 8: 293–312.CrossRefGoogle ScholarPubMed
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