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EPA-0492 - Functional Remediation in Bipolar II Patients: Improvement of Functioning and Subsyndromal Symptoms

Published online by Cambridge University Press:  15 April 2020

S. Brisa ,
CM. Bonnin ,
M. Mayoral ,
C. Torrent ,
BL. Amann ,
I. Torres ,
A. González-Pinto ,
E. Jiménez ,
JM. Crespo  and
F. Colom
...Show all authors
S. Brisa
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
CM. Bonnin
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
M. Mayoral
Affiliation:
Department of Psychiatry, Gregorio Marañón University General Hospital, Madrid, Spain
C. Torrent
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
BL. Amann
Affiliation:
FIDMAG, Research Foundation Germanes Hospitalàries, Barcelona, Spain
I. Torres
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
A. González-Pinto
Affiliation:
Álava University Hospital, University of the Basque Country Kronikgune, Vitoria, Spain
E. Jiménez
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
JM. Crespo
Affiliation:
Department of Psychiatry, University Hospital of Bellvitge, Barcelona, Spain
F. Colom
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
R. Tabarés-Seisdedos
Affiliation:
Department of Medicine, University of Valencia, Valencia, Spain
M. Reinares
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
J.L. Ayuso-Mateos
Affiliation:
Department of Psychiatry, Autonomous University of Madrid Research Institute of the Hospital de la Princesa, Madrid, Spain
S. Soria
Affiliation:
Department clinical Psychology, Hospital Universitari Clínic Universitat de Barcelona, Barcelona, Spain
M.P. Garcia-Portilla
Affiliation:
Department of Psychiatry, University of Oviedo, Oviedo, Spain
A. Ibáñez
Affiliation:
Department of Psychiatry, Ramon y Cajal Hospital Alcalá University IRYCIS, Madrid, Spain
E. Vieta
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
A. Martinez-Aran
Affiliation:
Barcelona Bipolar Disorders Program, Institute of Neuroscience University of Barcelona, Barcelona, Spain
G. Cibersam Functional Remediation
Affiliation:
Cibersam, Cibersam, Madrid, Spain

Abstract

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Introduction:

Recently, Functional Remediation (FR) has proven to be effective in improving the functional outcome of euthymic bipolar patients.

Objective:

Our objective was to test the efficacy of FR programme in a subsample of euthymic bipolar II patients (BPII).

Aims:

The main aim was improve the functional outcome in these patients.

Method:

Post-hoc analyses were undertaken using data of 53 DSM-IV diagnosed BPII outpatients who had participated in a multicentre, rater blind, randomized, controlled trial (RCT) exploring the efficacy of FR (n=17) as compared with a Psychoeducation (PSY) (n=19) and a control (n=17) groups which only treatment as usual (TAU). The primary outcome variable was a functional improvement measured as the mean change in the Functioning Assessment Short Test (FAST) from baseline to endpoint after intervention.

Results:

Data revealed a significant functional improvement from baseline to endpoint (Pillai's Trace =0.164; F =3.619; p =0.037), suggestive for an interaction between program pertinence and time (pre-post). Nevertheless, Tukey's post-hoc test only revealed a trend in favour of a better outcome for FR when compared to the TAU (p =0.058) and to the PSY group (p =0.062). We also found an interaction between program pertinence and time when analysing the subdepressive symptoms (Pillai's Trace =0.157; F =3.635; p =0.036), so that patients in FR showed a significant reduction in subdepressive symptomatology when compared to the PSY group (p= 0.041).

Conclusions:

The FR program appears to be effective in improving the overall functional outcome in BPII patients, as well as in reducing subdepressive symptoms.

Type
E07 - e-Poster Oral Session 07: Neurobiology, Bipolar Disorders and psychopathology
Information
European Psychiatry , Volume 29 , Issue S1: Abstracts of the 22nd European Congress of Psychiatry , 2014 , pp. 1
Copyright
Copyright © European Psychiatric Association 2014
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