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Methylphenidate Treatment in ADHD/borderline Personality Disorder Adolescent Girls and Smoking Behavior

Published online by Cambridge University Press:  16 April 2020

P. Golubchik ,
J. Sever ,
G. Shoval ,
G. Zalsman  and
A. Weizman
P. Golubchik
Affiliation:
Geha Mental Health Center, Beilinson Campus, Tel-Aviv University, Petah Tiqwa, Israel
J. Sever
Affiliation:
Geha Mental Health Center, Beilinson Campus, Tel-Aviv University, Petah Tiqwa, Israel
G. Shoval
Affiliation:
Geha Mental Health Center, Beilinson Campus, Tel-Aviv University, Petah Tiqwa, Israel
G. Zalsman
Affiliation:
Geha Mental Health Center, Beilinson Campus, Tel-Aviv University, Petah Tiqwa, Israel
A. Weizman
Affiliation:
Geha Mental Health Center, 5 Felsenstein Medical Research Center, Beilinson Campus, Tel-Aviv University, Petah Tiqwa, Israel

Abstract

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Background:

Cigarette smoking and nicotine dependence is prevalent among the attention deficit/hyperactivity disorder (ADHD) pediatric population. We assessed the influence of methylphenidate treatment on the smoking behavior of adolescent girls with ADHD/ borderline personality disorder (BPD).

Method:

Twelve ADHD/BPD female adolescent smokers aged 14-19 years were treated with MPH for an 8 week period. The severity of ADHD was assessed by the ADHD Rating Scale (ADHD-RS) and the smoking behavior was rated by Fagerstorm Test for Nicotine Dependence (FTND).

Results:

Significant improvement was detected in ADHD symptomathology, (Baseline vs. endpoint: ADHD-RS : 33.1±6.8 vs. 19.9±6.8, t=6.875, df=11, p=0.0001). A decline in the severity of nicotine dependence, as assessed by FTND (baseline vs. endpoint: 4.1±2.6 vs. 2.0±1.9, t = 4.056, df=11, p= 0.0019), was observed. No significant correlation was found between changes in the ADHD-RS and the FTND following methylphenidate treatment (r=0.09935, p=0.7587).

Conclusion:

Methylphenidate may attenuate smoking behavior in ADHD/BPD female adolescent smokers.

Type
S19-02
Information
European Psychiatry , Volume 24 , Issue S1: 17th EPA Congress - Lisbon, Portugal, January 2009, Abstract book , January 2009 , 24-E103
Copyright
Copyright © European Psychiatric Association 2009
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