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Pain, fatigability and cognitive impairment in log-COVID: a cohort study

Published online by Cambridge University Press:  27 August 2024

B. Nadia ,
T. Mariem ,
B. A. Houda ,
E. Sahar ,
A. Wissal ,
M. Sameh ,
K. Samy ,
H. Najla  and
A. Jihen
B. Nadia*
Affiliation:
1Psychiatry “B”
T. Mariem
Affiliation:
1Psychiatry “B”
B. A. Houda
Affiliation:
2Preventive medecine and hospital hygiene
E. Sahar
Affiliation:
1Psychiatry “B”
A. Wissal
Affiliation:
1Psychiatry “B”
M. Sameh
Affiliation:
3Pneumology, Hedi Chaker university hospital, Sfax, Tunisia
K. Samy
Affiliation:
3Pneumology, Hedi Chaker university hospital, Sfax, Tunisia
H. Najla
Affiliation:
1Psychiatry “B”
A. Jihen
Affiliation:
1Psychiatry “B”
*
*Corresponding author.

Abstract

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Introduction

Survivors of the pandemic of COVID-19 suffered from multiple sequelae long time after recovery, such as tiredness and memory dysfunction, affecting daily life activities.

Objectives

To assess fatigability, cognitive impairment and the severity of pain in long-COVID.

Methods

We conducted a prospective cohort study including 121 Tunisian COVID-19 inpatients who had been discharged alive from hospital. Each enrolled patient was asked about the period before the hospital stay, and the 6-9 month-period after hospital discharge, using the visual analog scale (VAS), self-completed unidimensional scale and yes/ no question about fatigability and cognitive impairments.

Results

The median age of participants was 59 years, with extreme values ranging from 18 to 80. Among them, 51.2% were females.

Our findings showed a significant increase in VAS score after COVID infection (3.82 vs 1.69; p<0.001). Sixty-eight (56.2%) participants reported spontaneously fatigability after the infection and 52 (43%) reported spontaneously a deterioration in memory capacity either with or without previous memory dysfunction. Fatigability was statistically associated to cognitive impairment (55.9% vs 26.4%; P= 0.02). In addition, fatigability and cognitive impairment were statistically associated with pain (P=0.001 and P= 0.022 respectively).

There was no significative association of fatigability nor cognitive impairment with the gender of the survivors.

Conclusions

The clinician should keep in mind to screen for possible somatic or psychological distress, in particular pain, fatigability and cognitive impairment even after resolution of the COVID infection, in order to guarantee a better quality of life.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S372 - S373
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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