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Regression models for biopsychosocial factors affecting patients with haemoglobinopathies in a Greek hospital

Published online by Cambridge University Press:  23 March 2020

G. Lyrakos ,
E. Aslani ,
V. Spinaris ,
M. Drossou-Servou  and
M. Tsironi
G. Lyrakos*
Affiliation:
General Hospital Nikaia “Ag. Panteleimon”, Psychiatric, Nikaia, Greece
E. Aslani
Affiliation:
University of Peloponnese Faculty of Human movement and Quality of Life Sciences, Department of Nursing, Sparti, Greece
V. Spinaris
Affiliation:
General Hospital Nikaia “Ag. Panteleimon”, Psychiatric, Nikaia, Greece
M. Drossou-Servou
Affiliation:
General Hospital Nikaia “Ag. Panteleimon”, Thalassemia Transfusion Unit, Nikaia, Greece
M. Tsironi
Affiliation:
University of Peloponnese Faculty of Human movement and Quality of Life Sciences, Department of Nursing, Sparti, Greece
*
*Corresponding author.

Abstract

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Introduction

Sickle cell and thalassemia (haemoglobinopathies) are autosomal recessive inherited conditions that affect haemoglobin and as chronic diseases, stress, anxiety and depression are comorbid conditions.

Objectives

To examine possible biopsychosocial factors affecting stress, anxiety and depression symptoms in these patients.

Aims

To investigate whether different condition related markers, contribute to the psychological symptomatology.

Methods

A total of 97 patients participated in the study, 21 males (21.6%) and 76 females (78.4%), with a mean age of 44.35. Convenience sampling method was used and participants were recruited from the General Hospital of Nikaia, ‘Ag. Panteleimon’, in Athens, Greece. DASS and MFI scales were used to measure the dependent and independent variables. Data were analysed with the SPSS 21 software.

Results

Multivariate analysis revealed that days between transfusions (beta = −0.454), reduced activity (beta = 0.350) and age (beta = −0.207) explained 30.1% of the variance in Stress [F(3.91) = 13.04 R2 = 0.301 P = 0.03]. Reduced activity (beta = 0.417) and days between transfusions (beta = 0.318) explained 30,3% of the variance in Anxiety [F(2.92) = 19.96 R2 = 0.301 P = 0.03]. Finally reduced activity (beta = 0.334), days between transfusions (beta = 0.364), and reduced motivation explained 41.3% of the variance in Depression [F(3.91) = 21.34 R2 = 0.413 P = 0.03]. Levels of ferritin, haemoglobin, age and present condition of health had a NS effect in the models.

Conclusions

Similar factors were found to affect stress, anxiety and depression in the sample, with days between transfusions and reduced activity being the major factors affecting the psychological symptoms in haemoglobinopathy patients. More research is needed in order for all the biopsychosocial factors to be revealed in this field.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster viewing: anxiety disorders and somatoform disorders
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S411 - S412
Copyright
Copyright © European Psychiatric Association 2017
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