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S09-01 - Nicotine Dependence, Psychological Distress, Personality Traits as Possible Predictors of Smoking Cessation. Results of a Double-Blind Study with Nicotine Patch

Published online by Cambridge University Press:  17 April 2020

F. Cosci ,
A. Corlando ,
E. Fornai ,
F. Pistelli ,
P. Paoletti  and
L. Carrozzi
F. Cosci
Affiliation:
Department of Psychology, University of Florence, Florence, Italy
A. Corlando
Affiliation:
Unit of Pulmonary Environmental Epidemiology, CNR Institute of Clinical Physiology, Italy
E. Fornai
Affiliation:
Unit of Pulmonary Environmental Epidemiology, CNR Institute of Clinical Physiology, Italy
F. Pistelli
Affiliation:
Unit of Pulmonary Environmental Epidemiology, CNR Institute of Clinical Physiology, Italy Cardio-Thoracic Department, University Hospital of Pisa, Pisa, Italy
P. Paoletti
Affiliation:
Glaxo Smith Kline, Philadelphia, PA, USA
L. Carrozzi
Affiliation:
Unit of Pulmonary Environmental Epidemiology, CNR Institute of Clinical Physiology, Italy Cardio-Thoracic Department, University Hospital of Pisa, Pisa, Italy

Abstract

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Objectives

Although Nicotine replacement therapy (NRT) is an effective treatment for smokers who want to quit, the rates of smoking cessation can be still improved. In an effort to increase these proportions, factors that may influence the occurrence of relapse have been increasingly studied (e.g. pharmacotherapy, socio-demographic characteristics) and there has been a growing interest in psychological and psychiatric clinical factors.

Methods

Nicotine dependence (assessed via the Fagerström Tolerance Questionnaire, FTQ), psychological distress (measured via the Symptom Rating Test, SRT), and personality traits (evaluated via the Adult Eysenck Personality Inventory, AEPI) were evaluated as possible predictors of smoking cessation in a sample of 297 cigarette smokers followed for one year as part of a NRT double-blind, parallel group, randomized trial.

Results

Baseline nicotine dependence (weeks 12 and 26: p < 0.05), AEPI neuroticism (weeks 12 and 52: p < 0.05), and AEPI psychoticism (weeks 12 and 52: p < 0.05) scores significantly influenced the outcome of smoking cessation during one - year of follow-up. An increase in psychological distress during follow-up was associated with a lower probability of quitting smoking (p = 0.000).

Conclusions

Nicotine dependence, neuroticism, psychoticism and, over time, psychological distress were the main factors influencing the long-term outcome (i.e., up to 12 months) of smoking cessation under NRT. Thus, psychological distress and personality characteristics should be evaluated in smokers who apply for assistance in smoking cessation with the aim to have a complete assessment and propose tailor-made interventions.

Type
The contribution of YPs in the excellence of European Psychiatric Research, a research prize winners symposium
Information
European Psychiatry , Volume 25 , Issue S1: 18th European Congress of Psychiatry. February 27, March 2, 2010 - Munich, Germany , 2010 , 25-E108
Copyright
Copyright © European Psychiatric Association 2010
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