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Chlorhexidine Does Not Select for Resistance in Staphylococcus aureus Isolates in a Community Setting

Published online by Cambridge University Press:  02 January 2015

Mark D. Johnson ,
Carey D. Schlett ,
Greg A. Grandits ,
Katrin Mende ,
Timothy J. Whitman ,
David R. Tribble ,
Duane R. Hospenthal  and
Patrick R. Murray
Mark D. Johnson
Affiliation:
Division of Infectious Diseases, Naval Medical Center, San Diego, California
Carey D. Schlett
Affiliation:
Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland
Greg A. Grandits
Affiliation:
Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota
Katrin Mende
Affiliation:
Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Texas
Timothy J. Whitman*
Affiliation:
Division of Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, Maryland
David R. Tribble
Affiliation:
Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland
Duane R. Hospenthal
Affiliation:
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Texas
Patrick R. Murray
Affiliation:
National Institutes of Health, Bethesda, Maryland
*
Infectious Diseases Department, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889 (timothy.whitman@med.navy.mil)
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Abstract

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Type
Letters to the Editor
Information
Infection Control & Hospital Epidemiology , Volume 33 , Issue 10 , October 2012 , pp. 1061 - 1063
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2012

References

1.Gorwitz, RJ, Jernigan, DB, Powers, JH, Jernigan, JA; Participants in the Centers for Disease Control and Prevention Convened Experts' Meeting on Management of MRSA in the Community. Strategies for Clinical Management of MRSA in the Community: Summary of an Experts' Meeting Convened by the Centers for Disease Control and Prevention. Atlanta: Centers for Disease Control and Prevention, 2006.Google Scholar
2.Milstone, AM, Passaretti, CL, Perl, TM. Chlorhexidine: expanding the armamentarium for infection control and prevention. Clin Infect Dis 2008;46(2):274–281.Google Scholar
3.Wang, JT, Sheng, WH, Wang, JL, et al.Longitudinal analysis of Chlorhexidine susceptibilities of nosocomial methicillin-resistant Staphylococcus aureus isolates at a teaching hospital in Taiwan. J Antimicrob Chemother 2008;62(3):514–517.Google Scholar
4.Longtin, J, Seah, C, Siebert, K, et al.Distribution of antiseptic-resistance genes qacA/B and smr in methicillin-resistant Staphylococcus aureus isolated in Toronto, 2005–2009. Antimicrob Agents Chemother 2011;2999–3001.Google Scholar
5.Whitman, TJ, Herlihy, RK, Schlett, CD, et al.Chlorhexidine-impregnated cloths to prevent skin and soft-tissue infection in Marine recruits: a cluster-randomized, double-blind, controlled effectiveness trial. Infect Control Hosp Epidemiol 2010;31(12):1207–1215.Google Scholar
6.Clinical and Laboratory Standards Institute (CLSI). Methods for Dilution: Antimicrobial Susceptibility Test for Bacteria that Grow Aerobically: Approved Standard; Seventh Edition. Wayne, PA: CLSI; 2006. CLSI document M07-A7.Google Scholar
7.Cookson, BD, Bolton, MC, Platt, JH. Chlorhexidine resistance in methicillin-resistant Staphylococcus aureus or just an elevated MIC? an in vitro and in vivo assessment. Antimicrob Agents Chemother 1991;35(10):1997–2002.Google Scholar
8.Noguchi, N, Hase, M, Kitta, M, Sasatsu, M, Deguchi, K, Kono, M. Antiseptic susceptibility and distribution of antiseptic-resistance genes in methicillin-resistant Staphylococcus aureus. FEMS Microbiol Lett 1999;172(2):247–253.Google Scholar
9.Ridenour, G, Lampen, R, Federspiel, J, Kritchevsky, S, Wong, E, Climo, M. Selective use of intranasal mupirocin and Chlorhexidine bathing and the incidence of methicillin-resistant Staphylococcus aureus colonization and infection among intensive care unit patients. Infect Control Hosp Epidemiol 2007;28(10):1155–1161.Google Scholar
10.Harbarth, S, Dharan, S, Liassine, N, Herrault, P, Auckenthaler, R, Pittet, D. Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 1999;43(6):1412–1416.Google Scholar