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Intranasal octenidine for methicillin-resistant Staphylococcus aureus (MRSA) carriers and universal octenidine bathing reduced MRSA acquisition in an acute-care general ward

Published online by Cambridge University Press:  16 July 2021

Aung-Hein Aung
Affiliation:
Department of Clinical Epidemiology, Office of Clinical Epidemiology, Analytics and Knowledge, Tan Tock Seng Hospital, Singapore
Win Mar Kyaw
Affiliation:
Department of Clinical Epidemiology, Office of Clinical Epidemiology, Analytics and Knowledge, Tan Tock Seng Hospital, Singapore
Yee Kiat Heng
Affiliation:
National Skin Centre, Singapore
Hong Liang Tey
Affiliation:
National Skin Centre, Singapore Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Brenda Ang
Affiliation:
Department of Infection Prevention and Control, Tan Tock Seng Hospital, Singapore
Angela Chow*
Affiliation:
Department of Clinical Epidemiology, Office of Clinical Epidemiology, Analytics and Knowledge, Tan Tock Seng Hospital, Singapore Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
*
Author for correspondence: Angela Chow, E-mail: angela_chow@ttsh.com.sg

Abstract

In this quasi-experimental before-and-after study in a methicillin-resistant staphylococcus aureus (MRSA) high-prevalence acute-care dermatology ward from August 2016 to November 2018, patients admitted during intervention period who received additional topical intranasal octenidine were 63% less likely to acquire MRSA than those receiving universal daily octenidine bathing alone during baseline period (aOR, 0.37; 95% CI, 0.14–0.98).

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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