Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-10T05:11:38.294Z Has data issue: false hasContentIssue false
  • English
  • Français

Nosocomial transmission of a blaVIM-2 carbapenemase integron between isolates of two different Pseudomonas species

Published online by Cambridge University Press:  19 February 2021

Andrea C. Büchler Open the ORCID record for Andrea C. Büchler [Opens in a new window] ,
Daniel Wüthrich ,
Melanie Wicki Jauslin ,
Adrian Egli  and
Andreas F. Widmer
Andrea C. Büchler
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
Daniel Wüthrich
Affiliation:
Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland
Melanie Wicki Jauslin
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
Adrian Egli
Affiliation:
Division of Clinical Bacteriology and Mycology, University Hospital Basel, Basel, Switzerland Applied Microbiology Research, Department of Biomedicine, University of Basel, Basel, Switzerland
Andreas F. Widmer*
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
*
Author for correspondence: Andreas F. Widmer, E-mail: andreas.widmer@usb.ch
Get access Rights & Permissions [Opens in a new window]

Abstract

We report the first documented in-hospital patient-to-patient-transmission of a blaVIM-2 integron between isolates of Pseudomonas alcaligenes and P. aeruginosa. Molecular typing looking only for difference within species may fail to detect nosocomial transmission of resistance genes.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 43 , Issue 2 , February 2022 , pp. 245 - 247
Check for updates
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baxter, R, Hastings, N, Law, A, Glass, EJ. Guidelines for the Prevention and Control of Carbapenem-Resistant Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa in Health Care Facilities. Geneva: World Health Organization; 2017.Google Scholar
Voor, AF, Severin, JA, Hagenaars, MBH, De, Goeij I, Gommers, D, Vos, MC. VIM-positive Pseudomonas aeruginosa in a large tertiary-care hospital: matched case- control studies and a network analysis. Antimicrob Resist Infect Control 2018;7(32):1–10.Google Scholar
Verfaillie, C, Bruno, M, F. Voor in’t holt, A, et al. Withdrawal of a novel-design duodenoscope ends outbreak of a VIM-2-producing Pseudomonas aeruginosa . Endoscopy 2015;47:493–502.Google ScholarPubMed
Price, D, Ahearn, DG. Incidence and persistence of Pseudomonas aeruginosa in whirlpools. J Clin Microbiol 1988;26:1650–1654.CrossRefGoogle ScholarPubMed
Kossow, A, Kampmeier, S, Willems, S, et al. Control of multidrug-resistant Pseudomonas aeruginosa in allogeneic hematopoietic stem cell transplant recipients by a novel bundle including remodeling of sanitary and water supply systems. Clin Infect Dis 2017;65:935–942.CrossRefGoogle ScholarPubMed
Suzuki, M, Suzuki, S, Matsui, M, Hiraki, Y, Kawano, F, Shibayama, K. Genome sequence of a strain of the human pathogenic bacterium Pseudomonas alcaligenes that caused bloodstream infection. Genome Announc 2013;1(5):1–2.CrossRefGoogle ScholarPubMed
Wick, RR, Judd, LM, Gorrie, CL, Holt, KE. Unicycler: resolving bacterial genome assemblies from short and long sequencing reads. PLoS Comput Biol 2017;13(6):1–22.CrossRefGoogle Scholar
Rutherford, K, Parkhill, J, Crook, J, et al. Artemis: sequence visualization and annotation. Bioinformatics 2000;16:944–945.CrossRefGoogle ScholarPubMed
Gouy, M, Guindon, S, Gascuel, O. Sea view version 4: a multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Mol Biol Evol 2010;27:221–224.10.1093/molbev/msp259CrossRefGoogle Scholar
Erb, S, Frei, R, Dangel, M, Widmer, AF. Multidrug-resistant organisms detected more than 48 hours after hospital admission are not necessarily hospital acquired. Infect Control Hosp Epidemiol 2017;38:18–23.CrossRefGoogle Scholar
Carbapenem resistenz. Anresis - Schweizerisches Zentrum für Antibiotikaresistenzen website. https://www.anresis.ch/de/antibiotikaresistenz/resistance-data-human-medicine/. Accessed October 14, 2020.Google Scholar