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Outbreak of Vancomycin-Resistant Enterococcus faecium in a Neonatal Intensive Care Unit

Published online by Cambridge University Press:  02 January 2015

Mark E. Rupp ,
Nedra Marion ,
Paul D. Fey ,
David L. Bolam ,
Peter C. Iwen ,
Christine M. Overfelt  and
Lucinda Chapman
Mark E. Rupp*
Affiliation:
Department of Internal Medicine, Nebraska Health System, Omaha, Nebraska Department of Healthcare Epidemiology, Nebraska Health System, Omaha, Nebraska
Nedra Marion
Affiliation:
Department of Healthcare Epidemiology, Nebraska Health System, Omaha, Nebraska
Paul D. Fey
Affiliation:
Department of Internal Medicine, Nebraska Health System, Omaha, Nebraska Department of Pathology and Microbiology, Nebraska Health System, Omaha, Nebraska Department of Healthcare Epidemiology, Nebraska Health System, Omaha, Nebraska
David L. Bolam
Affiliation:
Department of Pediatrics, University of Nebraska Medical Center, Nebraska Health System, Omaha, Nebraska
Peter C. Iwen
Affiliation:
Department of Pathology and Microbiology, Nebraska Health System, Omaha, Nebraska
Christine M. Overfelt
Affiliation:
Department of Nursing, Nebraska Health System, Omaha, Nebraska
Lucinda Chapman
Affiliation:
Department of Nursing, Nebraska Health System, Omaha, Nebraska
*
984031 Nebraska Medical Center, Omaha, NE 681998-4031
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Abstract

An outbreak of vancomycin-resistant Enterococcus faecium involving 28 infants in a neonatal intensive care unit was observed. Successful control of the outbreak was achieved following use of patient and staff cohorting, contact isolation precautions, patient and environmental surveillance cultures, environmental decontamination, molecular typing, introduction of an alcohol-based hand disinfectant, and decreased use of vancomycin.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 22 , Issue 5 , May 2001 , pp. 301 - 303
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2001

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References

1.Centers for Disease Control and Prevention. National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990-May 1999, issued June 1999. Am J Infect Control 1999;27:520–532.CrossRefGoogle Scholar
2.Singh-Naz, N, Sleemi, A, Pikis, A, Patel, K, Campos, J. Vancomycin-resistant Enterococcus faecium colonization in children. J Clin Microbiol 1999;37:413–416.CrossRefGoogle ScholarPubMed
3.Henning, K, Delencastre, H, Eagan, J, Boone, N, Brown, A, Chung, M, et al. Vancomycin-resistant Enterococcus faecium on a pediatric oncology ward: duration of stool shedding and incidence of clinical infection. Pediatr Infect Dis J 1996;15:848–854.Google Scholar
4.McNeeley, DF, Brown, AE, Noel, GJ, Chung, M, Lencastre, H. An investigation of vancomycin-resistant Enterococcus faecium within the pediatric service of a large urban medical center. Pediatr Infect Dis J 1998;17:184–188.CrossRefGoogle ScholarPubMed
5.Lee, HK, Lee, WG, Cho, SR. Clinical and molecular biological analysis of a nosocomial outbreak of vancomycin-resistant enterococci in a neonatal intensive care unit. Acta Paediatr 1999;88:651–654.Google Scholar
6.Malik, RK, Montecalvo, MA, Reale, MR, Li, K, Maw, M, Munoz, JL, et al. Epidemiology and control of vancomycin-resistant enterococci in a regional neonatal intensive care unit. Pediatr Infect Dis J 1999;18:352–356.Google Scholar
7.Iwen, P, Kelly, DM, Under, J, Hinrichs, S. Revised approach for identification and detection of ampicillin and vancomycin resistance in Enterococcus species by using MicroScan panels. J Clin Microbiol 1996;34:1779–1783.Google Scholar
8.National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. NCCLS document M100-S11. Villanova, PA: NCCLS; 2000.Google Scholar
9.Murray, BE, Singh, KV, Heath, JD, Sharma, BR, Weinstock, GM. Comparison of genomic DNAs of different enterococcal isolates using restriction endonucleases with infrequent recognition sites. J Clin Microbiol 1990;28:2059–2063.CrossRefGoogle ScholarPubMed
10.Falk, PS, Winnike, J, Woodmansee, C, Desai, M, Mayhall, CG. Outbreak of vancomycin-resistant enterococci in a burn unit. Infect Control Hosp Epidemiol 2000;21:575–582.Google Scholar
11.Wendt, C, Wiesenthal, B, Dietz, E, Ruden, H. Survival of vancomycin-resistant and vancomycin-susceptible enterococci on dry surfaces. J Clin Microbiol 1998;36:3734–3736.CrossRefGoogle ScholarPubMed
12.Murante, LJ, Kwapniowski, LA, Deines, T, Marion, N, Rupp, ME. Impact of a vancomycin-utilization educational program at a university teaching hospital. Presented at the Ninth Annual Scientific Meeting of the Society for Healthcare Epidemiology of America; April 1999; San Francisco, California. Abstract M57.Google Scholar
13.Harbarth, S, Sudre, P, Dharan, S, Cadenas, M, Pittet, D. Outbreak of Enterobacter cloacae related to understating, overcrowding, and poor hygiene practices. Infect Control Hosp Epidemiol 1999;20:598–603.Google Scholar