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Post-discharge decolonization of patients harboring methicillin-resistant Staphylococcus aureus (MRSA) USA300 strains: secondary analysis of the CLEAR Trial

Published online by Cambridge University Press:  16 December 2021

Gabrielle M. Gussin Open the ORCID record for Gabrielle M. Gussin [Opens in a new window] ,
Lauren Heim ,
Thomas Tjoa ,
James A. McKinnell ,
Loren G. Miller ,
Daniel L. Gillen ,
Mohamad R.A. Sater Open the ORCID record for Mohamad R.A. Sater [Opens in a new window] ,
Yonatan H. Grad Open the ORCID record for Yonatan H. Grad [Opens in a new window] ,
Raveena D. Singh  and
Susan S. Huang Open the ORCID record for Susan S. Huang [Opens in a new window]
Gabrielle M. Gussin*
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
Lauren Heim
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
Thomas Tjoa
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
James A. McKinnell
Affiliation:
Infectious Diseases, Lundquist Institute, Harbor-UCLA Medical Center, Torrance, CA, USA
Loren G. Miller
Affiliation:
Infectious Diseases, Lundquist Institute, Harbor-UCLA Medical Center, Torrance, CA, USA
Daniel L. Gillen
Affiliation:
Statistics, University of California, Irvine, Irvine, CA, USA
Mohamad R.A. Sater
Affiliation:
Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, MA, USA
Yonatan H. Grad
Affiliation:
Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, MA, USA
Raveena D. Singh
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
Susan S. Huang
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
*
Author for correspondence: Gabrielle M. Gussin, E-mail: gussing@hs.uci.edu
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Abstract

The CLEAR Trial recently found that decolonization reduced infections and hospitalizations in MRSA carriers in the year following hospital discharge. In this secondary analysis, we explored whether decolonization had a similar benefit in the subgroup of trial participants who harbored USA300, using two different definitions for the USA300 strain-type.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 2 , February 2023 , pp. 315 - 318
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

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