Hostname: page-component-745bb68f8f-b6zl4 Total loading time: 0 Render date: 2025-01-07T10:50:27.924Z Has data issue: false hasContentIssue false
  • English
  • Français

Similar duration of viral shedding of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) delta variant between vaccinated and incompletely vaccinated individuals

Part of: SARS-CoV-2/COVID-19

Published online by Cambridge University Press:  23 May 2022

Christopher E. Kandel Open the ORCID record for Christopher E. Kandel [Opens in a new window] ,
Andra Banete ,
Maureen Taylor Open the ORCID record for Maureen Taylor [Opens in a new window] ,
Andrea Llanes ,
Janine McCready ,
Gloria Crowl ,
Matthew Young ,
Angel X. Li ,
Emily Chien  and
Winfield Yim
...Show all authors
Christopher E. Kandel*
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
Andra Banete
Affiliation:
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Maureen Taylor
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
Andrea Llanes
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
Janine McCready
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
Gloria Crowl
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
Matthew Young
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
Angel X. Li
Affiliation:
Sinai Health System, Toronto, Ontario, Canada
Emily Chien
Affiliation:
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Winfield Yim
Affiliation:
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Lily Yip
Affiliation:
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Robert Kozak
Affiliation:
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Allison J. McGeer
Affiliation:
Sinai Health System, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Samira Mubareka
Affiliation:
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Jeff E. Powis
Affiliation:
Michael Garron Hospital, Toronto, Ontario, M4C 3E7, Canada
*
Author for correspondence: Dr. Christopher Kandel, E-mail: christopher.kandel@mail.utoronto.ca
Get access Rights & Permissions [Opens in a new window]

Abstract

Among outpatients with coronavirus disease 2019 (COVID-19) due to the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) δ (delta) variant who did and did not receive 2 vaccine doses at 7 days after symptom onset, there was no difference in viral shedding (cycle threshold difference 0.59, 95% CI, −4.68 to 3.50; P = .77) with SARS-CoV-2 cultured from 2 (7%) of 28 and 1 (4%) of 26 outpatients, respectively.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 6 , June 2023 , pp. 1002 - 1004
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Fisman, DN, Tuite, AR. Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada. CMAJ 2021;193:E1619–E1625.10.1503/cmaj.211248CrossRefGoogle ScholarPubMed
Kissler, SM, Fauver, JR, Mack, C, et al. Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies. PLoS Biol 2021;19:e3001333.10.1371/journal.pbio.3001333CrossRefGoogle Scholar
Walsh, KA, Jordan, K, Clyne, B, et al. SARS-CoV-2 detection, viral load and infectivity over the course of an infection. J Infect 2020;81:357–371.CrossRefGoogle ScholarPubMed
Cevik, M, Tate, M, Lloyd, O, Maraolo, AE, Schafers, J, Ho, A. SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis. Lancet Microbe 2021;2:e13–e22.10.1016/S2666-5247(20)30172-5CrossRefGoogle ScholarPubMed
Singanayagam, A, Hakki, S, Dunning, J, et al. Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study. Lancet Infect Dis 2022;22:183–195.CrossRefGoogle Scholar
Kissler, SM, Fauver, JR, Mack, C, et al. Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated persons. N Engl J Med 2021;385:2489–2491.CrossRefGoogle ScholarPubMed
Kandel, CE, Young, M, Serbanescu, MA, et al. Detection of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in outpatients: a multicenter comparison of self-collected saline gargle, oral swab, and combined oral-anterior nasal swab to a provider collected nasopharyngeal swab. Infect Control Hosp Epidemiol 2021;42:1340–1344.CrossRefGoogle ScholarPubMed
Kotwa, JD, Jamal, AJ, Mbareche, H, et al. Surface and air contamination with SARS-CoV-2 from hospitalized COVID-19 patients in Toronto, Canada, March–May 2020. J Infect Dis 2022;225:768–776.CrossRefGoogle Scholar
Chia, PY, Xiang Ong, SW, Chiew, CJ, et al. Virological and serological kinetics of SARS-CoV-2 delta variant vaccine-breakthrough infections: a multi-center cohort study. Clin Microbiol Infect 2022;28:612.e1–612.e7.10.1016/j.cmi.2021.11.010CrossRefGoogle Scholar
Puhach, O, Adea, K, Hulo, N et al. Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, delta and omicron. Nat Med 2022. doi: 10.1038/s41591-022-01816-0.CrossRefGoogle Scholar
Supplementary material: File

Kandel et al. supplementary material

Kandel et al. supplementary material

Download Kandel et al. supplementary material(File)
File 14 KB