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Topics in Clinical Microbiology Histopathologic Diagnosis of Fungal Diseases

Published online by Cambridge University Press:  02 January 2015

Charles W. Stratton  and
Michael O'Hare
Michael O'Hare*
Affiliation:
Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee
*
Department of Pathology, Vanderbilt University School of Medicine, Nashville, TN 31232
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Extract

There has been a tremendous increase in the number of immunocompromised patients over the past few decades, which has resulted in an increased number of serious fungal infections. These infections frequently require an invasive procedure, such as bone, lung, or lymph node biopsy, in order to obtain tissue for diagnosis. Far too often the tissue obtained by such means is not optimally utilized. For example, the tissue may be placed in formalin without being appropriately cultured, or the incorrect choice of tissue stains may result in the pathogen either being missed or being incorrectly identified. Clearly, this problem should be addressed by both the pathologist and the clinician.

Type
Special Sections
Information
Infection Control & Hospital Epidemiology , Volume 7 , Issue 2 , February 1986 , pp. 78 - 84
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1986

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References

1.Emmons, CW, Binford, CH. Utz, JP, et al (eds): Medical Mycology. Philadelphia, Lea and Febiger, 1977.Google Scholar
2.Brewer, NS. Weed, LA, Diagnostic tissue microbiology methods. Hum Pathol 1976;7:141–149.CrossRefGoogle ScholarPubMed
3.Robboy, SI, Vichery, AL, Tinctorial and morphologic properties distinguishing actinomycosis and nocardiosis. N Engl J Med 1970;292:593–596.CrossRefGoogle Scholar
4.Pickett, JP, Roggli, VL, Rapid histologic staining procedures for material from immune-suppressed patients. Am J Med Technol 1982;48:893–902.Google ScholarPubMed
5.Felegie, TP, Pasculle, AW, Recognition of Pneumocystis carinii in tissue impression smears by gram stain. Abstract No C98. Presented at the 83rd Annual Meeting of the American Society of Microbiology. New Orleans. Louisiana. 1983.Google Scholar
6.Macher, AM, Shelhamer, J, MacLowry, J, et al: Pneumocystis carinii identified by gram stain of lung imprints. Ann Intern Med 1983;99:484–485.CrossRefGoogle ScholarPubMed
7.Macher, AM, Shelhamer, J, Parrillio, J, et al: Prospective assessment of a new simple rapid stain: Modified methylene blue stain. Abstract No 87. Presented at the 23rd Interscience Conference on Antimicrobial Agents and Chemotherapy. Las Vegas, Nevada, 1983.Google Scholar
8.Monheil, JE, Cowan, DF, Moore, DC, Rapid detection of fungi in tissues using calcofluor white and fluorescence microscopy. Arch Pathol Lab Med 1984;108:616–618.Google Scholar
9.Schwarz, J, The diagnosis of deep mycoses by morphologic methods. Hum Pathol 1982;13:519–533.CrossRefGoogle ScholarPubMed