Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-11T08:41:49.040Z Has data issue: false hasContentIssue false
  • English
  • Français

Sectorial substrate-integrated half-mode near-field sensors for biological liquid characterization

Published online by Cambridge University Press:  01 April 2014

Nora Meyne  and
Arne F. Jacob
Nora Meyne*
Affiliation:
Institut für Hochfrequenztechnik, Technische Universität Hamburg-Harburg, 21073 Hamburg, Germany. Phone: +49 (0)40-42878-2225
Arne F. Jacob
Affiliation:
Institut für Hochfrequenztechnik, Technische Universität Hamburg-Harburg, 21073 Hamburg, Germany. Phone: +49 (0)40-42878-2225
*
Corresponding author N. Meyne Email: nora.meyne@tuhh.de
Get access Rights & Permissions [Opens in a new window]

Abstract

Two compact resonant near-field sensors are introduced for the characterization of aqueous solutions at 5 GHz. They are based on folded substrate-integrate circular half-mode resonators with a planar sensing tip. Owing to the planar design, the sensor is simple and cheap to manufacture, and a sample can be easily coupled to the resonator from the top. The operating principle of the sensor is explained and verified by both simulation and measurement. The radiation of the sensors is quantified by means of a quality factor analysis. Finally, a previously introduced calibration method based on the perturbation theory is applied to the sensors and its accuracy is improved by choosing more suitable reference materials.

Keywords

Medical and biological effectsCharacterization of material parameters
Type
Research Paper
Information
International Journal of Microwave and Wireless Technologies , Volume 6 , Issue 3-4: European Microwave Week 2013 , June 2014 , pp. 305 - 312
Copyright
Copyright © Cambridge University Press and the European Microwave Association 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

[1]Schwan, H.: Electrical properties of tissues and cell suspensions: mechanisms and models, in Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proc. 16th Annual Int. Conf. of the IEEE, November 1994, A70–A71.Google Scholar
[2]Booth, J.; Orloff, N.; Mateu, J.; Janezic, M.; Rinehart, M.; Beall, J.: Quantitative permittivity measurements of nanoliter liquid volumes in microfluidic channels to 40 GHz. IEEE Trans. Instrum. Meas., 59 (12) (2010), 3279–3288.Google Scholar
[3]Chen, T.; Dubuc, D.; Poupot, M.; Fournie, J.-J.; Grenier, K.: Accurate nanoliter liquid characterization up to 40 GHz for biomedical applications: toward noninvasive living cells monitoring. IEEE Trans. Microw. Theory Tech., 60 (12) (2012), 1–7.Google Scholar
[4]Ferrier, G.A.; Romanuik, S.F.; Thomson, D.J.; Bridges, G.E.; Freeman, M.R.: A microwave interferometric system for simultaneous actuation and detection of single biological cells. Lab Chip, 9 (2009), 3406–3412.CrossRefGoogle ScholarPubMed
[5]Chretiennot, T.; Dubuc, D.; Grenier, K.: A microwave and microfluidic planar resonator for efficient and accurate complex permittivity characterization of aqueous solutions. IEEE Trans. Microw. Theory Tech., 61 (2) (2013), 972–978.Google Scholar
[6]Ambrozkiewicz, M.; Jacob, A.F.: Substrate integrated resonant near-field sensor for material characterization, in 2010 IEEE MTT-S Int. Microwave Symp. Digest (MTT), 23–28 May 2010, 628–631.CrossRefGoogle Scholar
[7]Anlage, S.M.; Talanov, V.V.; Schwartz, A.R.: Principles of Near-Field Microwave Microscopy in Scanning Probe Microscopy Part I, Springer, New York, 2007, 215–253.Google Scholar
[8]Rosner, B.T.; van der Weide, D.W.: High-frequency near-field microscopy. Rev. Sci. Instrum., 73 (7) (2002), 2505–2525.Google Scholar
[9]Tselev, A.; Anlage, S.M.; Christen, H.M.; Moreland, R.L.; Talanov, V.V.; Schwartz, A.R.: Near-field microwave microscope with improved sensitivity and spatial resolution. Rev. Sci. Instrum., 74 (6) (2003), 3167–3170.Google Scholar
[10]Hong, W.; Gong, K.: Miniaturization of substrate integrated bandpass filters, in 2010 Asia-Pacific Microwave Conf. Proc. (APMC), 247–250.Google Scholar
[11]Huang, G.-S.; Chen, C.H.: Nonuniformly folded waveguide resonators and their filter applications. IEEE Microw. Wirel. Compon. Lett., 20 (3) (2010), 136–138.Google Scholar
[12]Zhai, G.H. et al. : Folded half mode substrate integrated waveguide 3 dB coupler. IEEE Microw. Wirel. Compon. Lett., 18 (8) (2008), 512–514.Google Scholar
[13]Sanz Izquierdo, B.; Young, P.; Grigoropoulos, N.; Batchelor, J.; Langley, R.: Substrate-integrated folded waveguide slot antenna, in IEEE Int. Workshop on Antenna Technology: Small Antennas and Novel Metamaterials, 2005. IWAT 2005., March 2005, 307–309.Google Scholar
[14]Haase, N.; Jacob, A.F.: Characterization of biological substances using a substrate integrated microwave near-field sensor, in 2012 42nd European Microwave Conf. (EuMC), October 29–November 1 2012, 432–435.CrossRefGoogle Scholar
[15]Grigoropoulos, N.; Sanz-Izquierdo, B.; Young, P.: Substrate integrated folded waveguides (SIFW) and filters. IEEE Microw. Wirel. Compon. Lett., 15 (12) (2005), 829–831.Google Scholar
[16]Uchimura, H.; Takenoshita, T.; Fujii, M.: Development of a laminated waveguide. IEEE Trans. Microw. Theory Tech., 46 (12) (1998), 2438–2443.Google Scholar
[17]Haase, N.; Jacob, A.F.: Substrate-Integrated Half-Mode Resonant Near-Field sensor for liquid characterization, in 2013 43rd European Microwave Conf. (EuMC), October 06–12 2013.Google Scholar
[18]Haase, N.; Jacob, A.F.: Dielectric contrast measurements on biological substances with resonant microwave near-field sensors. Int. J. Microw. Wirel. Technol., 5 (03) (2013), 221–230.Google Scholar
[19]Haase, N.; Jacob, A.F.: Resonant Substrate-Integrated Near-Field sensors with improved sensitivity, in 2013 43rd European Microwave Conf. (EuMC), October 06–12 2013.Google Scholar
[20]ANSYS® HFSS. www.ansys.com.Google Scholar
[21]Balanis, C.A.: Advanced Engineering Electromagnetics, John Wiley & Sons, Inc., Hoboken, New Jersey, 1989.Google Scholar
[22]Kajfez, D.; Chebolu, S.; Abdul-Gaffoor, M.R.; Kishk, A.A.: Uncertainty analysis of the transmission-type measurement of Q-factor. IEEE Trans. Microw. Theory Tech., 47 (1999), 367–371.Google Scholar
[23]Mongia, R.K.; Ittipiboon, A.; Cuhaci, M.: Measurement of radiation efficiency of dielectric resonator antennas. IEEE Microw. Guid. Wave Lett., 4 (3) (1994), 80–82.Google Scholar
[24]Stogryn, A.: Equations for calculating the dielectric constant of saline water. IEEE Trans. Microw. Theory Tech., 19 (1971), 733–736.CrossRefGoogle Scholar
[25]Kaatze, U.: Complex permittivity of water as a function of frequency and temperature. J. Chem. Eng. Data, 34 (1989), 371–374.CrossRefGoogle Scholar
[26]Rogers® Corporation Advanced Circuit Materials. www.rogerscorp.com.Google Scholar
[27]Pozar, D.M.: Microwave Engineering, 3rd ed., John Wiley & Sons, Inc., Hoboken, New Jersey, 2005.Google Scholar
[28]Collin, R.E.: Foundations for Microwave Engineering, McGraw-Hill, Inc., New York, 1966.Google Scholar