Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-15T16:57:08.015Z Has data issue: false hasContentIssue false
  • English
  • Français

Outcome after Asphyxial and Circulatory Disturbances in the Brain

Published online by Cambridge University Press:  10 March 2009

Malcolm I. Levene
Malcolm I. Levene
Affiliation:
Leicester Royal Infirmary
Get access Rights & Permissions [Opens in a new window]

Extract

The first consideration must be an agreed-upon definition of asphyxia. We cannot determine outcome of a condition if some observers are referring to apples and others to pears. Asphyxia is a pathophysiological event comprising both hypoperfusion and hypoxia, and these events result in compromise at a cellular level with the production of metabolic acids. This can be due to a wide number of insults, but a complication of the birth process is the most important cause. Asphyxia is not like intraventricular hemorrhage (IVH) or periventricular leukomalacia (PVL), as these are conditions that can be diagnosed with a reasonable degree of precision with imaging techniques.

Type
Neonatal Disorders of the Central Nervous System
Information
International Journal of Technology Assessment in Health Care , Volume 7 , Supplement S1 , January 1991 , pp. 113 - 117
Copyright
Copyright © Cambridge University Press 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1.Archer, L. N. J., Evans, D. H., & Levene, M. I.Cerebral artery Doppler ultrasonography for prediction of outcome after perinatal asphyxia. Lancet, 1986, ii, 1116–19.CrossRefGoogle Scholar
2.Ergander, U., Eriksson, M., & Zetterström, R.Severe neonatal asphyxia. Incidence and prediction of outcome in the Stockholm area. Acta Paediatrica Scandinavica, 1983, 72, 321–25.CrossRefGoogle ScholarPubMed
3.Finer, N. N., Robertson, C. M., Richards, R. T., Pinnell, L. E., & Peters, K. L.Hypoxic-ischemic encephalopathy in term neonates: perinatal factors and outcome. Journal of Pediatrics, 1981, 98, 112–17.CrossRefGoogle Scholar
4.Fysh, W. J., Turner, G. M., & Dunn, P. M.Neurological normality after extreme birth asphyxia. Case report. British Journal of Obstetrics and Gynaecology, 1982, 89, 24–26.CrossRefGoogle ScholarPubMed
5.Levene, M. I., Kornberg, J., & Williams, T. H.The incidence and severity of post-asphyxial encephalopathy in full-term infants. Early Human Development, 1985, 11, 21–28.CrossRefGoogle ScholarPubMed
6.Levene, M. I., Sands, C., Grindulis, H., & Moore, J. R.Comparison of two methods of predicting outcome in perinatal asphyxia. Lancet, 1986, i, 67–71.CrossRefGoogle Scholar
7.Lipper, E. G., Voorhies, T. M., Ross, G., Vannuccci, R. C., & Auld, P. A.Early predictors of one-year outcome for infants asphyxiated at birth. Developmental Medicine and Child Neurology, 1986, 28, 303–9.CrossRefGoogle ScholarPubMed
8.Low, J. A., Galbraith, R. S., Muir, D. W., Killen, H. L., Pater, E. A., & Karchmar, E. J.The relationship between perinatal hypoxia and newborn encephalopathy. American Journal of Obstetrics and Gynecology, 1985, 152, 256–60.CrossRefGoogle ScholarPubMed
9.Mulligan, J. C., Painter, M. J., O’Donoghue, P. A., MacDonald, H. M., & Allan, A. C.Neonatal asphyxia. II. Neonatal mortality and long-term sequelae. Journal of Pediatrics, 1980, 96, 903–7.CrossRefGoogle ScholarPubMed
10.Nelson, K. B., & Ellenberg, J. H.Apgar scores as predictors of chronic neurological disability. Pediatrics, 1981, 68, 36–44.CrossRefGoogle Scholar
11.Robertson, C., & Finer, N.Term infants with hypoxic-ischemic encephalopathy: Outcome at 3.5 years. Developmental Medicine and Child Neurology, 1985, 27, 473–84.CrossRefGoogle ScholarPubMed
12.Sarnat, H. B., & Sarnat, M. S.Neonatal encephalopathy following fetal distress. Archives of Neurology, 1976, 33, 696–705.CrossRefGoogle ScholarPubMed
13.Steiner, H., & Neligan, G.Perinatal cardiac arrest. Quality of the survivors. Archives of Diseases in Childhood, 1975, 50, 696–702.CrossRefGoogle ScholarPubMed
14.Thomson, A. J., Searle, M., & Russell, G.Quality of survival after severe birth asphyxia. Archives of Diseases in Childhood, 1977, 52, 620–26.CrossRefGoogle ScholarPubMed