Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-10T16:11:43.460Z Has data issue: false hasContentIssue false
  • English
  • Français

Effect of plant quinones on insect flight muscle mitochondria

Published online by Cambridge University Press:  19 September 2011

E. N. Magiri ,
V. N. Konji ,
D. W. Makawiti  and
J. Midiwo
E. N. Magiri
Affiliation:
Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
V. N. Konji
Affiliation:
Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
D. W. Makawiti
Affiliation:
Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
J. Midiwo
Affiliation:
Department of Chemistry, University of Nairobi, P.O. Box 30197, Nairobi, Kenya
Get access

Abstract

The effect of four biologically active and naturally occurring plant quinones, namely maesanin, maesaquinone, embelin and juglone on the respiration of mitochondria isolated from Glossina morsitans morsitans, Schistoscerca gregaria and Periplaneta americana was investigated. The rate of oxygen consumption by the mitochondria was measured using an oxygen electrode. Maesanin inhibited the mitochondrial electron transport chain at a level before cytochrome C whereas maesaquinone and embelin uncoupled the mitochondria. Juglone inhibited respiration in G. m. morsitans mitochondria and uncoupled those of S. gregaria and P. americana.

Résumé

L'effet de 4 quinones vegetales et actives biologiquements, notament maesanine, maesaquinone, embeline et juglone, a été étudié sur les mitochondries respiratoires isolées de Glossina morsitans morsitans, Schistocerca gregaria et Periplaneta americana. Le taux de consommation d'oxygène par les mitochondries a été mesurée à l'aide d'un electrode à oxygène. La maesanine a inhibé la chaine de transport de l'électron des mitochondries à un stade avant le cytochrome C tandis que le maesaquinone et l'embeline ont fait détacher la membrane mitochondriale. Le juglone a inhibé la respiration chez les mitochondries de G. m. morsitans et fait détacher celles de S. gregaria et P. americana.

Keywords

plant quinonesinsect flight muscle mitochondriarespirationquinones végétalesmitochondries des muscles de vol de l'insecterespiration
Type
Research Articles
Information
International Journal of Tropical Insect Science , Volume 16 , Issue 2 , June 1995 , pp. 183 - 189
Copyright
Copyright © ICIPE 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Addison, A. W., Cullen, W. R., Dolphin, D. and Janes, B. R. (1977) Biological Aspects of Inorganic Chemistry. Wiley Interscience, New York, Sydney, Toronto.Google Scholar
Bursell, E. (1975) Substrates of oxidative metabolism in dipteran flight muscle. Comp. Biochem. Physiol. 52, 235–238.Google ScholarPubMed
Bursell, E., Billing, K. C., Hagrove, J. W., McCabe, C. T. and Slack, E. (1974) Metabolism of blood meal in tsetse flies. Acta Trop. 31, 297–320.Google Scholar
Chander, H. and Ahmed, S. A. (185) Efficacy of natural embelin against the red flour beetle, Tribolium castaneum (Herbst). Insect Sci. Applic. 6, 217–220.CrossRefGoogle Scholar
Chander, H. and Ahmed, S. A. (1987) Laboratory evaluation of natural embelin as a grain protectant against some insect pests of wheat in storage. J. Stored Prod. Res. 23, 41–46.CrossRefGoogle Scholar
Dale, I. R. and Green way, P. J. (1961) Kenyan Trees and Shrubs Buchanan's Kenya Estates Ltd. Nairobi, 329 pp.Google Scholar
Deshmukh, S. D. and Borle, M. N. (1975) Studies on the insecticidal properties of indigenous products. Indian J. Ent. 37, 11–18.Google Scholar
Ernster, L. (1967) D.T. Diaphorase. In Methods in Enzymology (Edited by Estabrook, R. W. and Pullman, E. N.), Vol. 10, pp. 309–314. Academic Press, New York and London.Google Scholar
Huang, P., Chen, W. and Hu, Y. (1980) Studies on antituberculosis constituents from Ardisia japonica Sentii. China Inst. Bot. YaoHsueh Tung Pao, 15, 39.Google Scholar
Jacob, E. E. and Crane, F. L. (1960) Phosphorylation coupled to electron transport mediated by short chain derivatives of coenzymes A. Biochem. Biophys. Res. Commun. 2, 218–221.CrossRefGoogle Scholar
Lehninger, A. L. (1975) Biochemistry, Third Edition. Worth Publishers, Inc. New York.Google Scholar
Mabberley, D. J. (1987) The Plant Book. Cambridge University Press, Melbourne, Australia.Google Scholar
Midiwo, J. O., Arot, L. M. and Mbakaya, L. (1988) Distribution of benzoquinone pigments in Kenyan Myrsinacea. Bull. Chem. Soc. Ethiop. 2, 83–85.Google Scholar
Njagi, E. M. N. (1987) Transport and metabolism of proline and tricarboxylic acid cycle intermediate by the mitochondria of the tsetse fly Glossina morsitans. M.Sc. Thesis, University of Nairobi.Google Scholar
Ogawa, H. and Natoris, S. (1968) Hydroxybenzoquinones from Myrsinaceae. Plants—II. Phytochem. 7, 773–779.CrossRefGoogle Scholar
Rao, D. V., Rao, V. V. and Raghunada, P. (1985) Studies on embelin Part III. Synthesis and biological activity of some anthranilic acid ester derivatives of embelin and embelin-di-o-methyl ether. Indian J. Chem. 24, 988–991.Google Scholar
Richard, L. C. and Wang, J. H. (1970) Evidence of a phosphorylated intermediate in mitochondria oxidative phosphorylation. Biochem. Biophys. Res. Commun. 38, 848–854.Google Scholar
Shar, V., Sunder, R. and De Souza, N. J. (1984) Chornemorphine and rapanone antiparasite agents from plant source. J. Nat. Prod. 50, 730–731.Google Scholar
Slater, E. C. (1950) Application of inhibitors and uncouplers for a study of oxidative phosphorylation. In Methods in Enzymology (Edited by Estabrook, R. W. and Pullman, E. N.), Vol. 10, pp. 48–57. Academic Press, New York and London.Google Scholar
Webb, J. L. (1966) Quinones. In Enzyme and Metabolic Inhibitors (Edited by Webb, J. L.), Vol. 3, pp. 445–594. Academic Press, New York.Google Scholar