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Evidence for use of depot neuroleptic medication

Published online by Cambridge University Press:  13 June 2014

MacDara McCauley  and
Gerard Connolly
MacDara McCauley
Affiliation:
St Davnet's Hospital, Monaghan, Ireland
Gerard Connolly
Affiliation:
University College Dublin/Mater Hospital, Eccles St, Dublin 7, Ireland
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Abstract

Objective: To review the evidence guiding conventional and atypical depot neuroleptic usage.

Method: A search of biomedical electronic databases including Medline, Embase, PsychInfo and Cochrane was performed. Hand searching of journals was also carried out.

Results: Depot neuroleptics are safe and effective in the maintenance treatment of patients with schizophrenia. There is some evidence to support the use of depot neuroleptics in illnesses other than schizophrenia. The evidence base guiding depot usage is sparse.

Conclusions: Although guidelines are emerging there is a pressing need for rigorous well designed trials of depot antipsychotic usage. The advent of atypical depot antipsychotic preparations should stimulate research in this important area of clinical practice.

Keywords

DepotComplianceDoseFrequency
Type
Reviews
Information
Irish Journal of Psychological Medicine , Volume 21 , Issue 3 , September 2004 , pp. 95 - 99
Copyright
Copyright © Cambridge University Press 2004

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