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Korsakov

Published online by Cambridge University Press:  13 June 2014

Caoimhghin S Breathnach
Caoimhghin S Breathnach*
Affiliation:
Department of Physiology, University College Dublin, Earlsfort Terrace, Dublin 2
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Abstract

Alcoholic polyneuritis with characteristic mental symptoms was described by Sergei Korsakov in 1887; Wernicke confirmed and extended his observations, and modern high-resolution magnetic resonance imaging techniques make it possible to relate the confabulatory amnesia with abnormally small mammillary nuclei.

Keywords

KorsakovWernickeConfabulatory amnesiaEthanolThiamine deficiency
Type
Historical
Information
Irish Journal of Psychological Medicine , Volume 9 , Issue 1 , May 1992 , pp. 70 - 71
Copyright
Copyright © Cambridge University Press 1992

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References

1.Victor, M, Yakovlev, PI. S S Korsakoff's psychic disorder in association with peripheral neuritis. Neurology 1955; 5: 394–406.CrossRefGoogle Scholar
2.Gannt, WH, Muncie, W, Analysis of mental defect in chronic Korsakov's psychosis by means of conditioned reflex method. Bull Johns Hopkins Hosp 1942; 70: 467–487.Google Scholar
3.Squire, LR, Amaral, DG, Press, GA. Magnetic resonance imaging of the hippocampal formation and mammillary nuclei distinguish medial temporal lobe and diencephalic amnesia. J Neuroscience, 1990; 10: 3106–3117.CrossRefGoogle ScholarPubMed