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Experimental Brugia pahangi and B. malayi infections of callitrichid primates

Published online by Cambridge University Press:  05 June 2009

D. A. Denham ,
R. R. Suswillo  and
C. M. Hetherington
D. A. Denham
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, England
R. R. Suswillo
Affiliation:
London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, England
C. M. Hetherington
Affiliation:
National Institute of Medical Research, The Ridgeway, London, NW7 1AA, England
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Abstract

The callitrichid primates, Callithrix jacchus jacchus (the marmoset) and Saguinus labiatus (the tamarin) were inoculated with infective larvae of Brugia malayi and B. pahangi. Microfilaraemia at low levels developed in 3 out of 4 C. j. jacchus infected with B. malayi and living or dead adult worms found in all 4. Only one of 4 C. j. jacchus became microfilaraemic (mf + ve) when given B. pahangi and adults were found in two. Of 4 S. labiatus given B. pahangi one became very lightly mf + ve and adults were found in 3. It is concluded that these animals are not suitable hosts for chemotherapeutic experiments.

Keywords

Brugia malayiBrugia pahangicallitrichid primatesCallithrix jacchus jacchusSaguinus labiatusmarmosetstamarins
Type
Research Article
Information
Journal of Helminthology , Volume 63 , Issue 2 , June 1989 , pp. 84 - 86
Copyright
Copyright © Cambridge University Press 1989

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