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Studies on Spirometra theileri (Baer, 1925) n. comb. 3. Acquired immunity to reinfection with plerocercoids in mice

Published online by Cambridge University Press:  05 June 2009

E. K. Opuni  and
R. L. Muller
E. K. Opuni
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, London WCIE 7HT
R. L. Muller
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, London WCIE 7HT
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Abstract

100 male T.O. strain laboratory mice were divided into 4 equal groups: (I) 25 were injected intramuscularly with an antigen prepared together with Freund's adjuvant; (II) 25 injected with antigen alone; (III) 25 infected subcutaneously with 8 live plerocercoids of the same species; (IV) 25 served as controls. 4 weeks later all mice were given 6 live plerocercoids orally. The presence of acquired immunity in group III was shown by a significant reduction in the numbers, size and motility of challenge worms. The host response was greater in all the immunized groups than in the controls.

Type
Research Article
Information
Journal of Helminthology , Volume 49 , Issue 3 , September 1975 , pp. 199 - 204
Copyright
Copyright © Cambridge University Press 1975

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