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Endoscopic resection of malignant sinonasal tumours with or without chemotherapy and radiotherapy

Published online by Cambridge University Press:  21 August 2012

I Tojima ,
T Ogawa ,
H Kouzaki ,
S Seno ,
M Shibayama  and
T Shimizu
I Tojima*
Affiliation:
Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan
T Ogawa
Affiliation:
Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan
H Kouzaki
Affiliation:
Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan
S Seno
Affiliation:
Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan
M Shibayama
Affiliation:
Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan
T Shimizu
Affiliation:
Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan
*
Address for correspondence: Dr Ichiro Tojima, Department of Otorhinolaryngology, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan Fax: +81 (0)77 548 2783 E-mail: itirotz@hotmail.com
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Abstract

Objective:

An increasing number of transnasal endoscopic surgical procedures are being performed, and these procedures are now also utilised in the management of malignant sinonasal tumours. This study aimed to evaluate the outcome of endoscopic resection of sinonasal malignancies, with or without chemotherapy and radiotherapy.

Methods:

Between 2000 and 2009, six patients with sinonasal malignancies (diagnosed on pre-operative biopsy) underwent endoscopic resection at our hospital. The histopathological diagnoses varied and included squamous cell carcinoma, olfactory neuroblastoma, chordoma, extramedullary plasmacytoma and haemangiopericytoma.

Results:

Surgical resection was combined with chemotherapy and/or radiotherapy in four cases. The mean follow-up period was 43 months. One patient suffered local recurrence of chordoma, 84 months after the first operation, but this was successfully treated with proton beam radiotherapy.

Conclusion:

These results suggest that endoscopic resection may be a valid alternative to conventional resection in selected cases of malignant sinonasal tumour.

Keywords

Surgical Navigation SystemParanasal SinusesNeoplasma MalignantEndoscopic Surgery
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 10 , October 2012 , pp. 1027 - 1032
Copyright
Copyright © JLO (1984) Limited 2012

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References

1Seno, S, Ogawa, T, Shibayama, M, Ogawa, F, Fukui, J, Owaki, S et al. Endoscopic sinus surgery for the odontogenic maxillary cysts. Rhinology 2009;47:305–9CrossRefGoogle ScholarPubMed
2Seno, S, Arikata, M, Sakurai, H, Owaki, S, Fukui, J, Suzuki, M et al. Endoscopic ligation of the sphenopalatine artery and the maxillary artery for the treatment of intractable posterior epistaxis. Am J Rhinol Allergy 2009;23:197–9CrossRefGoogle ScholarPubMed
3Stammberger, H, Anderhuber, W, Walch, C, Papaefthymiou, G. Possibilities and limitations of endoscopic management of nasal and paranasal sinus malignancies. Acta Otorhinolaryngol Belg 1999;53:199–205Google ScholarPubMed
4Roh, HJ, Batra, PS, Citardi, MJ, Lee, J, Bolger, WE, Lanza, DC. Endoscopic resection of sinonasal malignancies: a preliminary report. Am J Rhinol 2004;18:239–46CrossRefGoogle ScholarPubMed
5Nicolai, P, Battaglia, P, Bignami, M, Bolzoni, A, Delu, G, Khrais, T et al. Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol 2008;22:308–16CrossRefGoogle Scholar
6Nicolai, P, Castelnuovo, P, Lombardi, D, Battaglia, P, Bignami, M, Pianta, L et al. Role of endoscopic surgery in the management of selected malignant epithelial neoplasms of the naso-ethmoidal complex. Head Neck 2007;29:1075–82CrossRefGoogle ScholarPubMed
7Lund, V, Howard, DJ, Wei, WI. Endoscopic resection of malignant tumors of the nose and sinuses. Am J Rhinol 2007;21:89–94CrossRefGoogle ScholarPubMed
8Hanna, E, DeMonte, F, Ibrahim, S, Roberts, D, Levine, N, Kupferman, M. Endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. Arch Otolaryngol Head Neck Surg 2009;135:1219–24CrossRefGoogle ScholarPubMed
9Kühn, UM, Mann, WJ, Amedee, RG. Endonasal approach for nasal and paranasal sinus tumor removal. ORL J Otorhinolaryngol Relat Spec 2001;63:366–71CrossRefGoogle ScholarPubMed
10Podboj, J, Smid, L. Endoscopic surgery with curative intent for malignant tumors of the nose and paranasal sinuses. Eur J Surg Oncol 2007;33:1081–6CrossRefGoogle ScholarPubMed
11Batra, PS, Citardi, MJ, Worley, S, Lee, J, Lanza, DC. Resection of anterior skull base tumors: comparison of combined traditional and endoscopic techniques. Am J Rhinol 2005;19:521–8CrossRefGoogle ScholarPubMed
12Luong, A, Citardi, MJ, Batra, PS. Management of sinonasal malignant neoplasms: defining the role of endoscopy. Am J Rhinol Allergy 2010;24:150–5CrossRefGoogle ScholarPubMed
13Villaret, AB, Yakirevitch, A, Bizzoni, A, Bosio, R, Bignami, M, Pistochini, A et al. Endoscopic transnasal craniectomy in the management of selected sinonasal malignancies. Am J Rhinol Allergy 2010;24:60–5CrossRefGoogle ScholarPubMed
14McCutcheon, IE, Blacklock, JB, Weber, RS, DeMonte, F, Moser, RP, Byers, M et al. Anterior transcranial (craniofacial) resection of tumors of the paranasal sinuses: surgical technique and results. Neurosurgery 1996;38:471–80Google ScholarPubMed
15Nishino, H, Miyata, M, Morita, M, Ishikawa, K, Kanazawa, T, Ichimura, K. Combined therapy with conservative surgery, radiotherapy, and regional chemotherapy for maxillary sinus carcinoma. Cancer 2000;89:1925–323.0.CO;2-H>CrossRefGoogle ScholarPubMed