Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-10T12:56:49.991Z Has data issue: false hasContentIssue false
  • English
  • Français

A new magnetic resonance imaging scoring system for perilymphatic space appearance after intratympanic gadolinium injection, and its clinical application

Published online by Cambridge University Press:  07 February 2012

Z-M Fang ,
X Chen ,
X Gu ,
Y Liu ,
R Zhang ,
D-R Cao  and
H-G He
Z-M Fang
Affiliation:
Department of Imaging, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
X Chen*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
X Gu
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
Y Liu
Affiliation:
Department of Imaging, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
R Zhang
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
D-R Cao
Affiliation:
Department of Imaging, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China
H-G He
Affiliation:
Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
*
Address for correspondence: Dr Xi Chen, Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Fujian Medical University, 20 Cha Zhong Road, Tai Jiang District, Fuzhou 350005, Fujian Province, PR China Fax: +86 591 83318716 E-mail: chenxi3518@yahoo.cn
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

To establish a new magnetic resonance imaging scoring system for diagnosing endolymphatic hydrops.

Patients and methods:

A total of 214 ears of 107 patients were categorised into five groups: no symptoms, Ménière's disease, sudden deafness, delayed endolymphatic hydrops and other ear disorders. Gadolinium distribution within the labyrinth was scored separately and quantitatively by two radiologists. Multiple independent-sample non-parametric tests, Bayesian discriminant analysis, multivariate logistic regression and receiver operating characteristic curve analyses were performed.

Results:

The derived scoring model was highly accurate for diagnosing Ménière's disease and delayed endolymphatic hydrops. Two magnetic resonance imaging scoring methods for the perilymphatic space were proposed for the diagnosis of endolymphatic hydrops: a pre-1 value (a new variable that predicts individual probability) of more than 0.3982299, or a sum of all labyrinth component scores of less than 14.5.

Conclusion:

A convenient method is proposed which offers reliable radiological diagnostic criteria for Ménière's disease and delayed endolymphatic hydrops.

Keywords

Endolymphatic HydropsMagnetic Resonance ImagingCochleaVestibuleLabyrinthSemicircular CanalsGadolinium DTPA
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 5 , May 2012 , pp. 454 - 459
Copyright
Copyright © JLO (1984) Limited 2012

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Zou, J, Poe, D, Bjelke, B, Pyykko, I. Visualization of inner ear disorders with MRI in vivo: from animal models to human application. Acta Otolaryngol Suppl 2009;560:22–31CrossRefGoogle Scholar
2Nakashima, T, Naganawa, S, Sugiura, M, Teranishi, M, Sone, M, Hayashi, H et al. Visualization of endolymphatic hydrops in patients with Meniere's disease. Laryngoscope 2007;117:415–20CrossRefGoogle ScholarPubMed
3Fukuoka, H, Tsukada, K, Miyagawa, M, Oguchi, T, Takumi, Y, Sugiura, M et al. Semi-quantitative evaluation of endolymphatic hydrops by bilateral intratympanic gadolinium-based contrast agent (GBCA) administration with MRI for Meniere's disease. Acta Otolaryngol 2010;130:10–16CrossRefGoogle ScholarPubMed
4Counter, SA, Bjelke, B, Borg, E, Klason, T, Chen, Z, Duan, ML. Magnetic resonance imaging of the membranous labyrinth during in vivo gadolinium (Gd-DTPA-BMA) uptake in the normal and lesioned cochlea. Neuroreport 2000;11:3979–83CrossRefGoogle ScholarPubMed
5Fiorino, F, Pizzini, FB, Beltramello, A, Barbieri, F. MRI performed after intratympanic gadolinium administration in patients with Ménière's disease: correlation with symptoms and signs. Eur Arch Otorhinolaryngol 2011;268:181–7CrossRefGoogle ScholarPubMed
6Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Menière's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc. Otolaryngol Head Neck Surg 1995;113:181–5Google Scholar
7Klemm, E, Deutscher, A, Mösges, R. A present investigation of the epidemiology in idiopathic sudden sensorineural hearing loss [in German]. Laryngorhinootologie 2009;88:524–7CrossRefGoogle ScholarPubMed
8Nakashima, T, Naganawa, S, Pyykko, I, Gibson, WP, Sone, M, Nakata, S et al. Grading of endolymphatic hydrops using magnetic resonance imaging. Acta Otolaryngol Suppl 2009;560:5–8CrossRefGoogle Scholar